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Final ID: Poster #: CR-013

Ductus arteriosus calcification: histopathological correlation in 2 case

Purpose or Case Report: Ductus Arteriosus calcification is a relatively common, typically unreported feature on plain film radiography. The more recent literature quotes a prevalence on unenhanced CT of between 37-61% of children and a peak at the age of 6-10 years. Adult studies have shown that calcification of the ligamentum arteriosum can occur alone or be associated with atherosclerotic and/or granulomatous calcification. We report two cases in whom they were identified as incidental findings on forensic post mortem CT, for whom we obtained histological confirmation.

Case 1: An 8 month old child who died in non-suspicious circumstances had incidental ductal arteriosus calcification reported on post mortem CT, following unremarkable skeletal survey. Intimal mural calcification was reported on histology at autopsy.

Case 2: A 19 month old child who died of aspiration underwent full skeletal survey and PMCT as part of the pre-autopsy imaging assessment. The skeletal survey revealed incidental ductus arteriosus calcification, initially reported as PDA clip, with correlation at CT. Intimal and medial mural calcification was reported on histology at autopsy.

These cases showed that ductal calcification was intimal and medial in nature. This is consistent with the current literature regarding mural calcification rather than thrombus regression calcification.
Methods & Materials:
Results:
Conclusions:
  • Chopra, Mark  ( Great Ormond Street Hospital , London , United Kingdom )
  • Barrett, Hannah  ( Great Ormond Street Hospital , London , United Kingdom )
  • Hutchinson, J.  ( Great Ormond Street Hospital , London , United Kingdom )
  • Kiho, Liina  ( Great Ormond Street Hospital , London , United Kingdom )
  • Arthurs, Owen  ( Great Ormond Street Hospital , London , United Kingdom )
Session Info:

Electronic Exhibits - Case Reports

Other

Scientific Exhibits - Case Reports

More abstracts on this topic:
More abstracts from these authors:
Ductus Arteriosus calcification: a literature review

Chopra Mark, Barrett Hannah, Hutchinson J., Kiho Liina, Arthurs Owen

Micro-CT in perinatal autopsy: changing diagnoses at early gestation.

Hutchinson J., Haig Ian, Sebire Neil, Arthurs Owen

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