Main Logo

Society for Pediatric Radiology – Poster Archive


Final ID: Paper #: 133

MRI Findings in CNS Manifestations of Leukemia

Purpose or Case Report: To identify the main neuroimaging findings using MRI on pediatric patients with known diagnosis of leukemia at our institution during a period of 4 years.
Methods & Materials: We retrospectively evaluated all patient with confirmed diagnosis of leukemia and included all patients with neurologic symptoms whom MRI were performed. Findings were divided in primary (effects related to leukemia) and secondary (therapeutic effects).
Results: From the 197 patients with Leukemia, 37 had clinical neurologic symptoms and imaging of the brain. The average age was 8.37 years (+/- 4.2), from 1.8 to 15 years old. 17 females, 20 males. We found 31 patients with Acute Lymphocytic Leukemia (ALL), 3 with Acute Myeloid Leukemia (AML) and 3 with Mixed-phenotype Acute Leukemia. Intense headache was the most common symptom reported in 16 patients, follow by epilepsy in 10 patients. In the group of manifestations of primary disease we had 19 findings, the main findings were meningeal infiltration (7), parenchymal hemorrhage (3), optic nerve infiltration (3) and chloroma (3). In the group of therapeutic effects we had 32 findings, being the most frequent cortical atrophy (12), parenchymal hemorrhage (6), PRES (5) and leukoencephalopathy (4).
Conclusions: The most frequent neuroimaging findings in patients with leukemia were related to therapeutic effects with cortical atrophy and parenchymal hemorrhage. These were followed by changes related to primary disease such as meningeal infiltration, parenchymal hemorrhage, optic nerve infiltration and chloroma. To be aware of more frequent CNS manifestations of leukemia is crucial for radiologists, in order to ensure an accurate diagnosis and prompt treatment.
Session Info:

Scientific Session V-B: Neuroradiology


SPR Scientific Papers

More abstracts on this topic:
A Practical Guide to MRI Evaluation of the Placenta

Brown Brandon, Shea Lindsey, Marine Megan

Antenatal US and MR features of Congenital High Airway Obstruction Sequence (CHAOS)

El Hawari Mohamad, Joshi Akash, Zarchan Adam, Dobbs-desilet Debbie, Ornelas Samuel

More abstracts from these authors:
Medidas Normales de la Laringe y Tráquea en Etapa Fetal por RM

Lazarte Claudia, Montero José, Mejia Richard, Huamani Jesus, Ugas-charcape Carlos

Anillos Vasculares: Serie de Casos y Aproximación para el Reporte Radiológico

Ugas Charcape Carlos, Matos-rojas Irma, Sanchez-navarro Juan P., Fernández-ochoa Diana, Conilla-arispe José M.

Due to circumstances surrounding the coronavirus pandemic, this final ePoster exhibit was not submitted.
You have to be authorized to contact abstract author. Please, Login or Signup.

Please note that this is a separate login, not connected with your credentials used for the SPR main website.

Not Available


We encourage you to join the discussion by posting your comments and questions below.

Presenters will be notified of your post so that they can respond as appropriate.

This discussion platform is provided to foster engagement, and stimulate conversation and knowledge sharing.

Please click here to review the full terms and conditions for engaging in the discussion, including refraining from product promotion and non-constructive feedback.


You have to be authorized to post a comment. Please, Login or Signup.

Please note that this is a separate login, not connected with your credentials used for the SPR main website.

   Rate this abstract  (Maximum characters: 500)