Not Available
Society for Pediatric Radiology – Poster Archive
Final ID: Paper #: 037
Pediatric Diagnostic Reference Ranges for Dual-energy Dual-source Contrast-enhanced Chest CT
Purpose or Case Report: To develop diagnostic reference ranges (DRRs) for pediatric contrast-enhanced dual-energy CT (DECT) examinations as a function of patient size and radiation output of the CT scanner with comparison to conventional single energy CT (SECT).
Methods & Materials: This is an institutional review board-approved, retrospective study which included pediatric patients (age 8.0 ± 6.6 years, range newborn to 21 years) undergoing contrast-enhanced chest CT with either SECT or DECT on a dual-source CT system (Somatom Flash, Siemens), from September 2014 until September 2018. Volume CT dose index (CTDIvol) and patient effective diameter were extracted using dose tracking software (Radimetrics): SECT (N=264) and DECT (N=291). All exams used automatic exposure control and iterative reconstruction. SECT used automated kilovoltage selection (range 80 to 120 kV), and DECT used 80/140Sn kV. Patient data were grouped into one of five effective diameter ranges to allow development of DDRs as a function of patient size. The median, 25th and 75th quartile of the two CT dose indexes were determined for the corresponding effective diameters. Quantitative image metrics assessed included contrast, noise and contrast-to-noise ratio. Subjective image quality (scale 1, excellent, to 4, non-diagnostic) of 10 DECT and SECT scans from each circumference group was assessed Statistical unpaired comparisons were made between groups.
Results: For the five effective diameters (< 15cm, 15-19cm, 20-24cm, 25-30 cm and > 30cm), the median CTDIvol [25th-75th quartile] for DECT were 1.2 [0.9-1.3], 1.7 [1.4-2.0], 3.0 [2.4-3.6], 5.0 [4.3-6.0], 7.7 [6.0-12.8] mGy; and for SECT 1.0 [0.7-1.4], 1.2 [1.0-1.7], 3.5[2.4-5.0], 6.3[4.9-7.3], 9.4[8.1-12.1] mGy; respectively. The CTDIvol values were statistically similar between SECT and DECT across all groups, except in the 20-24cm group where the CTDIvol for DECT was lower (P < 0.01). Quantitative and qualitative image quality was similar for both groups.
Conclusions: Dual energy CT can be used clinically in pediatric chest CT with radiation exposures and image quality similar to those of SECT. The DRRs (median, 25th and 75th quartiles) reported in this study as a function of patient size and radiation output can serve as reference standards to help manage pediatric patient radiation doses and image quality in DECT
Methods & Materials: This is an institutional review board-approved, retrospective study which included pediatric patients (age 8.0 ± 6.6 years, range newborn to 21 years) undergoing contrast-enhanced chest CT with either SECT or DECT on a dual-source CT system (Somatom Flash, Siemens), from September 2014 until September 2018. Volume CT dose index (CTDIvol) and patient effective diameter were extracted using dose tracking software (Radimetrics): SECT (N=264) and DECT (N=291). All exams used automatic exposure control and iterative reconstruction. SECT used automated kilovoltage selection (range 80 to 120 kV), and DECT used 80/140Sn kV. Patient data were grouped into one of five effective diameter ranges to allow development of DDRs as a function of patient size. The median, 25th and 75th quartile of the two CT dose indexes were determined for the corresponding effective diameters. Quantitative image metrics assessed included contrast, noise and contrast-to-noise ratio. Subjective image quality (scale 1, excellent, to 4, non-diagnostic) of 10 DECT and SECT scans from each circumference group was assessed Statistical unpaired comparisons were made between groups.
Results: For the five effective diameters (< 15cm, 15-19cm, 20-24cm, 25-30 cm and > 30cm), the median CTDIvol [25th-75th quartile] for DECT were 1.2 [0.9-1.3], 1.7 [1.4-2.0], 3.0 [2.4-3.6], 5.0 [4.3-6.0], 7.7 [6.0-12.8] mGy; and for SECT 1.0 [0.7-1.4], 1.2 [1.0-1.7], 3.5[2.4-5.0], 6.3[4.9-7.3], 9.4[8.1-12.1] mGy; respectively. The CTDIvol values were statistically similar between SECT and DECT across all groups, except in the 20-24cm group where the CTDIvol for DECT was lower (P < 0.01). Quantitative and qualitative image quality was similar for both groups.
Conclusions: Dual energy CT can be used clinically in pediatric chest CT with radiation exposures and image quality similar to those of SECT. The DRRs (median, 25th and 75th quartiles) reported in this study as a function of patient size and radiation output can serve as reference standards to help manage pediatric patient radiation doses and image quality in DECT
More abstracts on this topic:
Low Dose Imaging of Neonates with Congenital Cardiovascular Disease: Initial Experience with FLASH Computed Tomography Angiography (CTA)
Luhar Aarti, Vu Dan, Holmes Nathan, Renella Pierangelo
CT dose measurement and dose reduction techniques in cardiac and cardiovascular CT – What you really need to know...Semple Thomas, Schofield Rebecca, Petraco Da Cunha Ricardo, Owens Catherine, Nicol E, King Lawrence, Castellano I
Due to circumstances surrounding the coronavirus pandemic, this final ePoster exhibit was not submitted.
Comments
We encourage you to join the discussion by posting your comments and questions below.
Presenters will be notified of your post so that they can respond as appropriate.
This discussion platform is provided to foster engagement, and stimulate conversation and knowledge sharing.
Please click here to review the full terms and conditions for engaging in the discussion, including refraining from product promotion and non-constructive feedback.
You have to be authorized to post a comment. Please,
Login or
Signup.
Please note that this is a separate login, not connected with your credentials used for the SPR main website.
Rate this abstract
(Maximum characters: 500)
Please note that this is a separate login, not connected with your credentials used for the SPR main website.