Purpose or Case Report: Bones are frequent targets of various neoplastic and non-neoplastic disorders, which often present with focal bone pain. Clinicians should be familiar with the workup of a challenging symptom such as focal bone pain, in order to make appropriate referrals to various specialists, order appropriate investigations and tissue sampling workup, and avoid unnecessary prolonged antibiotics course, thereby preventing delay in diagnosis and antibiotics resistance.

Sometimes, results of various investigations are not always discriminatory among infectious, inflammatory, neoplastic and non-neoplastic etiologies. Some of these disorders can be a source of important morbidity and mortality in infants and children. In order to optimize diagnostic accuracy, early detection of diseases, detection of clinically silent lesions, and disease management, it is imperative for radiologists to be familiar with the imaging characteristics of each entity and the proper methods employed in their evaluation. In light of this, whole body imaging may be performed to get highest yield and cost effectiveness.

The purpose of this exhibit is:

■ To discuss the indications and highlight the role of Whole body MRI and Whole Body Bone Scan
■ To describe scan protocols of Whole body MRI and Whole Body Bone Scan
■ To describe the imaging appearance of some of the oncologic and non-oncologic diseases presenting as bone pain
■ To briefly compare Whole body MRI and Whole Body Bone Scan

Illustrative cases from our Radiology Department will be used to demonstrate various entities such as chronic recurrent multifocal osteomyelitis, infections, Langerhans cell histiocytosis, hematological malignancies, and bony metastases.
Methods & Materials:
Results:
Conclusions: