Purpose or Case Report: Thyroid cancer is the most prevalent endocrine malignancy in the pediatric population. Accurate diagnosis and staging of thyroid carcinoma demand a multimodality approach, including anatomic imaging with US, CT, and MRI, alongside functional or metabolic nuclear imaging. Novel imaging techniques such as US elastography, contrast-enhanced US (CEUS), superb microvascular imaging (SMI) and dual-source dual-energy thyroid CT have offered non-invasive tools to assess disease status. Furthermore, the emerging field of radiomics/radiogenomics and artificial intelligence is continuously growing, creating models to classify or predict disease behaviour. We provide a comprehensive overview of the essential imaging characteristics of pediatric thyroid carcinoma using conventional and novel imaging techniques. In addition, we illustrate the multimodality, multidisciplinary, and collaborative approach across pediatric radiology and nuclear medicine in pre-operative, post-operative and post-treatment imaging surveillance of cancer thyroid in children.
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