Purpose or Case Report: Posterior fossa tumours account for approximately 50% of the Pediatric CNS tumors. Major technological advances, mainly in the fields of molecular biology and neuroimaging, have modified their classification, leading to more detailed description of these entities in the most recent updated 2021 WHO Pediatric CNS Tumor Classification.

Unique neuroimaging characteristics mainly on MRI can provide precise diagnosis with molecular subtype. This exhibit highlights key neuroimaging features to guide the correct tumor diagnosis and molecular subtypes in the most common Pediatric Infratentorial Barin Tumors.
Methods & Materials: 1) Retrospective search of Radiology PACS at tertiary level children's hospital was done using key words " posterior fossa tumors", " pilocytic
astrocytoma", "medulloblastoma"," ependymona", " atypical teratoid rhabdoid tumor", "hemangioblastoma", etc.
2) Representative cases were identified and selected through the list to include in this educational exhibit.
3) To obtain a specific molecular diagnosis for each selected case, a meticulus search was done to look into detail patient tissue sample
pathology and immunohistochemical diagnosis.
4) Variety of Infratentorial Tumour mimics such as aracnoid cysts, dermoid/epidermoid cysts, pyogenic/granulomatous abscesses,vascular
malformations, were excluded from the study.
Results: 1) A set of common and uncommon Pediatric Infratentorial Brain Tumors and its mimics was generated with precise explanation to conquer
diagnostic dilemmas.
2) The exhibit helps develop a case based search pattern with respect to probable molecular diagnosis with confidence.
3) The neuroimaging guided approach towards diagnosis of infratentorial CNS brain tumors provides neurosergons with clear roadmap
towards timely and accurate patient management.
Conclusions: Accurate neuroimaging based diagnostic skillsets for Pediatric Infratentorial CNS Tumors were generated which will be helpful to trainees as well as attending pediatric neuroradiologists to guide further management plans with reasonable accuracy which is a real challange.