Purpose or Case Report: The role of locoregional therapy options (percutaneous thermal ablation, chemoembolization, and/or radioembolization) continues to gain traction in the pediatric oncology world, particularly with the management of primary and metastatic liver lesions. Post-treatment imaging of the liver must clearly differentiate between treatment response, residual untreated disease and progressive disease in order to guide the future therapeutic options.
The post-treatment imaging appearance of pediatric liver lesions can be affected by multiple factors (tumor type, tumor vascularity, radiation vs non-radiation therapy, background liver characteristics, time lapse from the interventional oncology procedure, imaging technique, e.g.). The understanding and interpretation of such factors continues to evolve, as seen with the most recent ACR LI-RADS Treatment Response Assessment Update in 2024. This case cohort presents illustrative examples from multiple pediatric interventional oncology programs, using various imaging modalities to demonstrate post-treatment liver imaging findings following locoregional therapy for both primary and metastatic liver lesions in pediatric patients.
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