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Society for Pediatric Radiology – Poster Archive


Sickle
Showing 3 Abstracts.

Taylor Erin,  Graeber Brendon,  Ehrlich Lauren

Final Pr. ID: Poster #: EDU-041

Sickle cell disease (SCD) is characterized by repeated episodes of vaso-occlusion and hemolysis beginning in the pediatric period that result in serious multi-organ system complications. In particular, renal complications are often the cause of morbidity and reduced life expectancy of patients with SCD. Therefore, it is essential that radiologists be able to identify the imaging features early to help guide prompt and appropriate treatment.

Sequelae in pediatric patients include sickle cell nephropathy, infarction and papillary necrosis, and assorted glomerulopathies. These in turn can lead to altered hemodynamics, impaired urinary concentrating ability, hematuria, proteinuria, and acute and chronic kidney injury. Children with SCD are also at increased risk of asymptomatic bacteriuria and urinary tract infection. Even those children and young adults who only have sickle cell trait (SCT) rather than SCD may develop chronic kidney disease later in life and carry markedly increased risk for renal medullary carcinoma. Segmental testicular infarction can compromise fertility in patients with both SCD and SCT.

The genitourinary manifestations of SCD and SCT in the pediatric patient will be reviewed in this educational exhibit, with an emphasis on radiologic appearances. For each entity, the clinical presentation, pathophysiology, and differential diagnosis of the imaging findings will also be briefly reviewed.

The renal complications covered will include renal infarction, papillary necrosis, renal vein thrombosis (as a complication of nephrotic syndrome), urinary tract infection, hematuria, renal medullary carcinoma, and acute and chronic kidney disease. Testicular and penile sequelae of SCD including segmental testicular infarction and priapism will also be discussed. A variety of imaging modalities will be used to illustrate the various complications, including ultrasonography, computed tomography, and magnetic resonance imaging.
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Authors:  Taylor Erin , Graeber Brendon , Ehrlich Lauren

Keywords:  Sickle, Renal, Genitourinary

Saulsberry-abate Anjelica,  Davis James,  Hryhorczuk Anastasia

Final Pr. ID: Poster #: EDU-058

Review the clinical presentation, imaging findings, and management of emergencies in children with sickle cell disease (SCD), with attention to the critical role of imaging when differentiating between potential diagnoses and directing appropriate care. This exhibit will explore the multimodality emergency imaging of children with:
I. Acute vasoocclusive pain crisis
II. Dactylitis
III. Infection/sepsis
IV. Acute chest syndrome
V. Stroke
VI. Splenic sequestration
VII. Gallbladder disease
VIII. Renal nephropathy and infarcts
We will emphasize the central role of imaging in identifying acute and life-threatening complications in children with sickle cell disease, as well as the value of radiology in uncovering other pathologic processes that should be considered when children with SCD present to the emergency department.
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Authors:  Saulsberry-abate Anjelica , Davis James , Hryhorczuk Anastasia

Keywords:  Sickle Cell, Emergency, Hematology

Kozak Brandi

Final Pr. ID: Poster #: EDU-018 (T)

Transcranial Doppler examinations are crucial in the care and treatment of patients in the Sickle cell population. The earlier we are able to obtain diagnostic studies on these patients the more effective treatment is and can reduce the risk of the patient suffering from a life altering stroke. Read More

Authors:  Kozak Brandi

Keywords:  Transcranial Doppler, TCD, Sickle Cell