Purpose or Case Report: In this educational exhibit we plan:
1. To identify and illustrate the spectrum of blastomas on various imaging modalities
2. To review the pathogenesis of these tumors
3. To describe and illustrate the typical and atypical imaging appearances and organ-wise differential diagnosis
Methods & Materials: Blastomas are rare childhood tumors that can affect any organ system in the body and at times can be devastating if left untreated. Controversy surrounds their nomenclature and there is no globally accepted classification. They are thought to arise from immature, primitive tissues with persistent embryonal elements on histology. These tumors affect a younger population and are usually malignant. Imaging is often non-specific but plays an important role in identification, management and follow-up. In this exhibit, we discuss the characteristic imaging features and pathogenesis of select blastomas.
Results: We will review the classification, pathogenesis and imaging features of the following lesions:

Ameloblastoma
Hamartoblastoma
Ganglioneuroblastoma
Neuroblastoma
Nephroblastoma
Hepatoblastoma
Medulloblastoma
Lipoblastoma
Osteoblastoma
Chondroblastoma
Hemangioblastoma
Gonadoblastoma
Sialoblastoma
Pleuropulmonary blastoma
Pancreatoblastoma
Pineoblastoma
Medullomyoblastoma
Conclusions: Blastomas are rare neoplasms and may have non-specific imaging appearances. They differ in epidemiology, clinical outcome, and prognosis. A high degree of clinical suspicion and familiarity with the various radiologic manifestations of blastomas allow early diagnosis and timely initiation of appropriate therapy, thereby reducing patient morbidity.