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Final ID: Poster #: CR-034

Vaping Associated Lung Injury Requiring Bilateral Lung Transplant in an Adolescent

Purpose or Case Report: E-cigarette, or vaping, product use associated lung injury (EVALI) is a newly recognized entity that is being reported with increasing frequency in the literature and mainstream press. The aim of this case report is to radiographically illustrate the fairly rapid progression of a severe case of EVALI that ultimately required a successful bilateral lung transplant, and to describe a unique histopathology correlation.

Case Report:
Our patient is a 16-year-old, previously healthy male with a two year history of vaping who presented to an outside hospital for dyspnea and nonproductive cough. He was initially treated with antibiotics for community acquired pneumonia. Initial contrast-enhanced CT of the chest demonstrated subtle bilateral but right lower lobe predominant centrilobular nodules, ground glass opacities (GGO) and mild septal thickening. Bronchial alveolar lavage, microbiology studies and autoimmune panel were negative for an infectious or autoimmune etiology. Repeat chest CT only five days later following clinical deterioration demonstrated a dramatic worsening of bilateral nodular airspace opacities, septal thickening, GGO and dependent diffuse consolidations. Pneumomediastinum and mild bronchiectasis were also present. Our patient’s condition continued to decline requiring intubation and subsequent ECMO support. He was transferred to our tertiary care center for bilateral lung transplant. Histopathology of the explanted lungs described predominant acute necrotizing and granulomatous bronchopneumonia with areas of organizing pneumonia.
Methods & Materials:
Results:
Conclusions:
  • Poyiadji, Neo  ( Henry Ford Health System , Northville , Michigan , United States )
  • Sabharwal, Gauravi  ( Henry Ford Health System , Northville , Michigan , United States )
  • Leschied, Jessica  ( Henry Ford Health System , Northville , Michigan , United States )
  • Ledbetter, Karyn  ( Henry Ford Health System , Northville , Michigan , United States )
  • Song, Tom  ( Henry Ford Health System , Northville , Michigan , United States )
  • Collins, Denise  ( Henry Ford Health System , Northville , Michigan , United States )
  • Montecalvo, Joseph  ( Henry Ford Health System , Northville , Michigan , United States )
Session Info:

Posters - Case Report

Thoracic Imaging

SPR Posters - Case Reports

More abstracts from these authors:
Imaging Findings of Hypoxic Ischemic Encephalopathy in Neonates: A Multimodality Imaging Review

Le Phong, Leschied Jessica, Ledbetter Karyn

What’s Old is New Again: A Case Series of Osseous Manifestations of Congenital Syphilis

Eteer Khalid, Collins Denise, Sabharwal Gauravi, Ledbetter Karyn, Leschied Jessica

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