Purpose or Case Report: Post mortem imaging provides non-invasive diagnostic insight into investigating fetal loss, complementing conventional examination. When post mortem examination of the brain is limited, post mortem MRI (PM MRI) can help further evaluate intracranial abnormalities not identified antenatally or via pathology.

We present PM MRI from a small cohort of cases acquired following initiation of a post mortem imaging service at our tertiary children’s hospital in the UK, demonstrating the value of this modality in comparison to antenatal ultrasound (US), and its concordance with formal pathological examination.

Illustrating both PM MRI and pathological findings from each case, we aim to (1) review the current guidance for post mortem MR imaging of fetuses in Europe and America, (2) highlight the importance of gestational age, weight and condition of the fetus when considering the best imaging modality, (3) compare images and sequences from both 1.5Tesla and 3Tesla MRI strength scanners and consider their diagnostic value, (4) showcase the most common PM MRI intracranial findings and (5) prove positive concordance with and diagnostic value to formal pathological investigations.


Following review, we hope the reader will have the knowledge and increased confidence to implement a post mortem MRI imaging service at their institution, recognising the value it can add to formal pathology examinations and subsequent diagnoses. Radiology-pathology relations and synergy give further opportunity to understand causes of fetal death, which is critical to helping grieving families and counsel those considering future pregnancy.
Methods & Materials:
Results:
Conclusions: