Showing 1 Abstract.
Traffic-Related Air Pollution Associated with Reduced Cortical Thickness and Altered White Matter Organization in a Longitudinally Studied, Pediatric Cohort
Cecil Kim, Ryan Patrick, Beckwith Travis, Altaye Mekibib, Severs Rachel, Wolfe Christopher, Percy Zana, Maloney Thomas, Yolton Kimberly, Lemasters Grace
Final Pr. ID: Poster #: SCI-049
Traffic-related air pollution (TRAP), a complex mixture of particulate matter, metals,
elemental and organic carbon, polycyclic aromatic hydrocarbons, and other constituents, is strongly associated with
cardiopulmonary health effects. Evidence suggests the developing brain may also be a target organ for these particles
due to translocation either from the respiratory system or through the olfactory nerve. Using an established pediatric
epidemiological cohort with extensive longitudinal exposure assessment since infancy, we tested the hypothesis that
exposure to TRAP during critical windows of brain development is significantly associated with changes in brain
structure and organization. Our imaging study design targeted recruitment of participants from the cohort with the
highest and lowest quartiles of exposure at time of birth.
Read More
Authors: Cecil Kim , Ryan Patrick , Beckwith Travis , Altaye Mekibib , Severs Rachel , Wolfe Christopher , Percy Zana , Maloney Thomas , Yolton Kimberly , Lemasters Grace