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Society for Pediatric Radiology – Poster Archive


Disease Severity
Showing 1 Abstract.

O'donovan Julie,  Murray Becky,  Hu Houchun,  Wallihan Rebecca,  Mejias Asuncion,  Ramilo Octavio,  Krishnamurthy Rajesh

Final Pr. ID: Poster #: SCI-069

CAP is a worldwide contributor to morbidity and mortality in children. Radiogenomics is an emerging specialty which correlates imaging features to gene expression to predict disease severity, therapeutic response and clinical outcomes. A genomic score termed Molecular Distance to Health (MDTH) is a biomarker that measures the global transcriptional perturbation in blood and has been shown to correlate with disease severity in pediatric CAP (Wallihan R, Front. Cell. Infect. Microbiol. 2018). This study was undertaken to determine whether abnormalities on chest radiographs correlate with genomic and clinical markers of disease severity. Read More

Authors:  O'donovan Julie , Murray Becky , Hu Houchun , Wallihan Rebecca , Mejias Asuncion , Ramilo Octavio , Krishnamurthy Rajesh

Keywords:  radiogenomics, disease severity, MDTH