Showing 3 Abstracts.
Combining chest radiographic findings and genomic scores to improve assessment of disease severity in pediatric community acquired pneumonia (CAP).
O'donovan Julie, Murray Becky, Hu Houchun, Wallihan Rebecca, Mejias Asuncion, Ramilo Octavio, Krishnamurthy Rajesh
Final Pr. ID: Poster #: SCI-069
CAP is a worldwide contributor to morbidity and mortality in children. Radiogenomics is an emerging specialty which correlates imaging features to gene expression to predict disease severity, therapeutic response and clinical outcomes. A genomic score termed Molecular Distance to Health (MDTH) is a biomarker that measures the global transcriptional perturbation in blood and has been shown to correlate with disease severity in pediatric CAP (Wallihan R, Front. Cell. Infect. Microbiol. 2018). This study was undertaken to determine whether abnormalities on chest radiographs correlate with genomic and clinical markers of disease severity. Read More
Authors: O'donovan Julie , Murray Becky , Hu Houchun , Wallihan Rebecca , Mejias Asuncion , Ramilo Octavio , Krishnamurthy Rajesh
Keywords: radiogenomics, disease severity, MDTH
Holroyd Alexandria, Khrichenko Dmitry, States Lisa
Final Pr. ID: Paper #: 157
Radiogenomics refers to the correlation of imaging and genomic data of tumors in cancer patients. This study attempts to make correlations between biomarkers in NGS Comprehensive Solid Tumor Panel reports and MRI imaging findings in neuroblastoma patients. Read More
Authors: Holroyd Alexandria , Khrichenko Dmitry , States Lisa
Keywords: Neuroblastoma, Radiogenomics
Radiogenomics of Pediatric Infratentorial Brain Tumor Based on the Most Recent 2021 WHO CNS Tumor Classification
Final Pr. ID: Poster #: EDU-095
Posterior fossa tumours account for approximately 50% of the Pediatric CNS tumors. Major technological advances, mainly in the fields of molecular biology and neuroimaging, have modified their classification, leading to more detailed description of these entities in the most recent updated 2021 WHO Pediatric CNS Tumor Classification.
Unique neuroimaging characteristics mainly on MRI can provide precise diagnosis with molecular subtype. This exhibit highlights key neuroimaging features to guide the correct tumor diagnosis and molecular subtypes in the most common Pediatric Infratentorial Barin Tumors.
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Authors: Kathiria Deepti
Keywords: Brain MRI, Radiogenomics, Posterior Cranial Fossa