Khrichenko Dmitry

Final Pr. ID: Poster #: EDU-018

Magnetic Resonance Imaging (MRI) R2 and R2* relaxometry has been shown to accurately quantify liver iron content (LIC) without the need for invasive biopsy. However, different post processing techniques and different calibration curves can lead to variability in the measured iron content. A detailed demonstration using the pMRI software package (www.parametricmri.com) of how to analyze R2 and R2* MRI relaxometry images to estimate LIC is presented. Linear monoexpoential, non-linear monoexpoential, biexponential and truncation models are used, compared and discussed. A selection of established LIC vs R2* calibration curves are compared in real time. Anonymized example cases of varying levels of iron overload are used to demonstrate segmentation techniques including region growing and semi-automatic vessel exclusion. After each analysis, a detailed LIC report is automatically generated and explained. Read More

Authors:  Khrichenko Dmitry

Keywords:  LIC, Post Processing, MRI

Ricci Kiersten,  Mobberley-schuman Paula,  Hammill Adrienne,  Dasgupta Roshni,  Patel Manish

Final Pr. ID: Poster #: SCI-031

Slow-flow vascular malformations, most commonly multifocal or diffuse venous (VM), venous-lymphatic (VLM) and capillary-lymphatic-venous malformations (CLVM), are associated with coagulation abnormalities affecting hemostasis and thrombosis and increase risk of hematological complications with procedural interventions. Although not completely understood, pathogenesis of this coagulopathy, termed localized intravascular coagulopathy (LIC), is presumed secondary to stagnant blood in abnormal vessels and consumption of coagulation factors. LIC is characterized by elevated D-dimer, low fibrinogen, and/or mild thrombocytopenia and may progress to disseminated intravascular coagulopathy following surgical procedures. In patients with high-risk malformations, hematologic complications of sclerotherapy and use of low molecular weight heparin (LMWH) as a preventative measure have not been well studied. Read More

Authors:  Ricci Kiersten , Mobberley-schuman Paula , Hammill Adrienne , Dasgupta Roshni , Patel Manish

Keywords:  LIC, Vasculat Malformation, Coagulopathy