Tokaria Rumana,  Jaramillo Diego

Final Pr. ID: Poster #: SCI-023

It is estimated that the ratio between the femoral and tibial growths is 0.94/0.67 (1.4), but the accuracy of the data used to obtain it is limited. We aim to find a correlation between the rate of new bone growth in between each zebra line in the patients with Osteogenesis Imperfects (OI) who have received cyclic bisphosphonate (BP) therapy with each treatment cycle between the distal tibia and proximal femur. This will allow us to quantify the growth of the distal femur and proximal tibia with accuracy. Read More

Authors:  Tokaria Rumana , Jaramillo Diego

Keywords:  Osteogenesis Imperfecta, zebra lines, growth rate

Yacoub Daniel,  Wang Kuan Chung,  Shah Prakeshkumar,  Moineddin Rahim,  Doria Andrea

Final Pr. ID: Poster #: SCI-063

Increased fracture risk is a complication that occurs in the context of primary bone diseases such as osteogenesis imperfecta (OI). Despite being considered as the reference-standard, the use of dual-energy X-ray absorptiometry (DXA) to evaluate fragility fractures in OI has not been validated by prior systemic review. Identifying patients at greatest risk for bone fragility fractures and determining skeletal health markers that can monitor bone mass concerning response to bone-active treatments are important issues for clinicians. In this systematic review we assessed the clinical utility of DXA for evaluating osteoporotic bone in OI pediatric patients according to the U.S. Preventive Services Task Force guidelines. Read More

Authors:  Yacoub Daniel , Wang Kuan Chung , Shah Prakeshkumar , Moineddin Rahim , Doria Andrea

Keywords:  Dual-energy X-ray absorptiometry (DXA), Osteogenesis imperfecta, Systematic review, Fracture, Clinimetric property

Illimoottil Mathew,  Errampalli Eric,  Kosaraju Sriya,  Priya Lakshmi,  Orscheln Emily

Final Pr. ID: Poster #: EDU-055

Osteogenesis imperfecta (OI) is a rare genetic disorder that affects bone development and structure, resulting in bone fragility and susceptibility to fractures. This educational exhibit offers a comprehensive examination of OI, with particular emphasis on the clinical types I, II, III, IV, and V. With a focus on diagnostic tools, management strategies, and emerging treatments, this exhibit aims to enhance the understanding of OI within the pediatric radiology community. We will present a detailed overview of OI types, emphasizing the genetic and clinical variations that distinguish them. Attendees will gain insights into the pathophysiology of OI and its impact on bone health, growth, and overall well-being in affected children. We will highlight imaging techniques and genetic testing that facilitate accurate diagnosis and characterization of OI types. Through case studies, we will demonstrate the pivotal role of radiologists in early detection and improved patient outcomes. Treatment modalities for OI, including bisphosphonates, orthopedic interventions, and emerging therapies, will be explored. Our goal is to empower pediatric radiologists with the knowledge and tools necessary to provide accurate and timely diagnosis as well as to contribute to optimal disease management, ongoing research,
and advancements in the field. By focusing on OI in all its diverse manifestations, this exhibit aims to strengthen the expertise of pediatric radiologists in identifying, characterizing, and managing this complex condition. Our collective effort in enhancing the care of children with OI will ultimately improve their quality of life and future prospects. Read More

Authors:  Illimoottil Mathew , Errampalli Eric , Kosaraju Sriya , Priya Lakshmi , Orscheln Emily

Keywords:  Osteogenesis Imperfecta