Edwards Harriet,  Mir Malaikah,  Mcpartland Jo

Final Pr. ID: Poster #: EDU-028

Post mortem imaging provides non-invasive diagnostic insight into investigating fetal loss, complementing conventional examination. When post mortem examination of the brain is limited, post mortem MRI (PM MRI) can help further evaluate intracranial abnormalities not identified antenatally or via pathology.

We present PM MRI from a small cohort of cases acquired following initiation of a post mortem imaging service at our tertiary children’s hospital in the UK, demonstrating the value of this modality in comparison to antenatal ultrasound (US), and its concordance with formal pathological examination.

Illustrating both PM MRI and pathological findings from each case, we aim to (1) review the current guidance for post mortem MR imaging of fetuses in Europe and America, (2) highlight the importance of gestational age, weight and condition of the fetus when considering the best imaging modality, (3) compare images and sequences from both 1.5Tesla and 3Tesla MRI strength scanners and consider their diagnostic value, (4) showcase the most common PM MRI intracranial findings and (5) prove positive concordance with and diagnostic value to formal pathological investigations.


Following review, we hope the reader will have the knowledge and increased confidence to implement a post mortem MRI imaging service at their institution, recognising the value it can add to formal pathology examinations and subsequent diagnoses. Radiology-pathology relations and synergy give further opportunity to understand causes of fetal death, which is critical to helping grieving families and counsel those considering future pregnancy. Read More

Authors:  Edwards Harriet , Mir Malaikah , Mcpartland Jo

Keywords:  Postmortem, Perinatal, Fetal Brain MRI

Tupprasoot Raksa,  Langan Dean,  Sury Mike,  Arthurs Owen

Final Pr. ID: Poster #: SCI-001

Endotracheal or nasotracheal intubation can be difficult in preterm infants in an intensive care environment, with a high rate of endobronchial tube placement. We measured tracheal length and diameter in a population of post mortem fetuses to define the relationship between gestational age or body weight and tracheal size, in order to see whether this could help future tube selection or correct placement. Read More

Authors:  Tupprasoot Raksa , Langan Dean , Sury Mike , Arthurs Owen

Keywords:  Trachea, perinatal, intubation, MRI

Llorens-salvador Roberto,  Veiga-canuto Diana

Final Pr. ID: Poster #: EDU-037

Short Bowel Syndrome (SBS) is a significant cause of morbidity and mortality in neonates, resulting from a substantial reduction in functional small intestine.
It may arise from congenital anomalies or acquired conditions requiring extensive bowel resection.
This educational exhibit presents a review of the different pathologies potentially leading to SBS in neonates, to help radiologists offer an early and accurate diagnosis, critical to optimize clinical outcomes.
We review and illustrate conditions using multimodality imaging in:
1. Congenital causes of SBD:
Gastroschisis.
Bowel atresia.
Complicated meconium ileus.
Meconium peritonitis and meconium pseudocyst.
2. Acquired causes of SBS:
Malrotation and midgut volvulus.
Necrotizing enterocolitis.
Hirschsprung’s disease.

This study aims to underscore the essential role of perinatal imaging in the early detection, characterization, and management planning of both congenital and acquired etiologies leading to SBS in the neonatal population.
Emphasis is placed on the diagnostic utility of prenatal ultrasound and MRI and postnatal imaging techniques starting with plain radiography, contrast studies, and cross-sectional imaging in the neonatal period. Read More

Authors:  Llorens-salvador Roberto , Veiga-canuto Diana

Keywords:  Prenatal Imaging, Neonatal Bowel Obstruction, Perinatal

Llorens-salvador Roberto,  Veiga-canuto Diana,  Ortega-lopez Pedro,  Navarro Oscar

Final Pr. ID: Poster #: EDU-029

HNF1B nephropathy is a hereditary renal disease caused by mutations in the HNF1B gene, transmitted in an autosomal dominant manner but frequently occurring as de novo mutations. This genetic variability complicates diagnosis, as family history of renal disease may be absent. Clinical presentation is heterogeneous, with onset in both children and adults, and may include renal dysfunction, metabolic abnormalities, and in some cases early-onset diabetes.

In the pediatric setting, imaging plays a crucial role in raising suspicion of HNF1B nephropathy. Prenatal ultrasound and MRI may reveal echogenic kidneys or renal hypoplasia in the third trimester, while postnatal ultrasound may show variable findings such as increased renal echogenicity, renal cysts, and reduced renal size. These abnormalities can mimic more common entities, highlighting the importance of a systematic imaging approach.

This educational exhibit reviews the prenatal and postnatal imaging findings of HNF1B nephropathy in children emphasizing key imaging clues that should raise diagnostic suspicion when encountering cystic or dysplastic renal patterns. The exhibit also includes discussion of the differential diagnosis with other conditions associated with renal cysts, such as autosomal dominant polycystic kidney disease (ADPKD), autosomal recessive polycystic kidney disease (ARPKD), multicystic renal dysplasia, Meckel–Gruber syndrome and other ciliopathies. Recognizing the imaging spectrum of HNF1B nephropathy is essential to avoid misclassification as nonspecific chronic interstitial nephropathy and to ensure timely genetic testing, counseling, and long-term multidisciplinary management. Read More

Authors:  Llorens-salvador Roberto , Veiga-canuto Diana , Ortega-lopez Pedro , Navarro Oscar

Keywords:  Perinatal, Kidneys, Cystic

Jones Chad,  Woodward Connor,  Woo Raymund,  Williams Jennifer

Final Pr. ID: Poster #: EDU-051

The overall incidence of birth trauma ranges from 2-3%, with the large majority consisting of superficial soft tissue injury. Musculoskeletal birth trauma tends to occur most commonly around the shoulder, with clavicle and brachial plexus injuries representing the majority of MSK trauma. Perinatal long bone fractures are quite rare, with most affecting the humeral/femoral diaphysis. Physeal fractures represent an even more uncommon entity and can be radiographically occult due to non-ossification of the epiphysis in neonates. In our educational poster, we present a variety of perinatal fractures of the physis which were initially occult on radiograph, but became evident on further workup with MR. Read More

Authors:  Jones Chad , Woodward Connor , Woo Raymund , Williams Jennifer

Keywords:  Fracture, Physis, Perinatal

Pérez-marrero Lizbet,  Castoldi Maria Francesca,  Fuentealba Isabel,  Stecher Ximena,  Schonstedt Valeria,  Cisternas Daniela,  Castiblanco Adriana,  Repetto Gabriela,  Legarraga Paulette,  Schultz Marcela

Final Pr. ID: Poster #: SCI-011

At our institution there is not possible to perform a perinatal autopsy. Also, there is usually parental resistance to this procedure, especially in cases of stillbirths or perinatal deaths. To address this issue, in 2018, we introduced a protocol of Postmortem Perinatal MRI (PPMRI) in cases where no known or suspected cause of death was identified in antenatal studies, and the gestational age exceeded 22 weeks. This communication aims to share our experience with the utilization of PPMRI, either as a standalone diagnostic tool or as part of a minimally invasive autopsy protocol. Read More

Authors:  Pérez-marrero Lizbet , Castoldi Maria Francesca , Fuentealba Isabel , Stecher Ximena , Schonstedt Valeria , Cisternas Daniela , Castiblanco Adriana , Repetto Gabriela , Legarraga Paulette , Schultz Marcela

Keywords:  Postmortem Perinatal MRI, perinatal autopsy, stillbirths