High T1 and T2 relaxivity macrocyclic gadolinium-based contrast agents (GBCAs), including gadopiclenol, have the potential to improve contrast-enhanced MRI while minimizing Gd dose. However, administered at low volumes in pediatric joint arthrography, the in vivo concentration of GBCA is variable due to pathological and anatomical volume differences. Concentration variations in conjunction with rapid T2 decay inherent to highly relaxive GBCAs can result in variable signal. To determine optimal dosages, we tested concentration-dependent signal changes in phantom studies with T1-weighted (T1w) and T2-weighted (T2w) sequences commonly used in clinical arthrogram studies. Read More

Meeting name: IPR 2026 Congress , 2026

Authors: Arellano Cameron, Colon Rodney, Hobollah Sarah, Bhandari Prajwal, Ghaghada Ketan, Annapragada Ananth, Badachhape Andrew

Keywords: Arthrography, Contrast MRI, Glenohumeral