Systemic lupus erythematosus (SLE) is a generalized autoimmune connective tissue disease which can cause white-matter micro-architectural changes in the central nervous system. Further, involvement appears to be independent of the presence or absence of neuropsychiatric symptoms. However, these findings have largely been elucidated in adults with an overall paucity of data regarding white-matter micro-architectural changes in the pediatric SLE population. The purpose of this study is to objectively identify the presence of white-matter micro-architectural changes in pediatric patients with SLE compared to age-matched healthy controls. Read More

Meeting name: SPR 2024 Annual Meeting & Postgraduate Course , 2024

Authors: Epps Caleb, Chu Zili, Desai Nilesh, Huisman Thierry, Beil Emily, Muscal Eyal, Kralik Stephen

Keywords: Systemic lupus erythematosus, Diffuse tractography, Fractional anisotropy