To illustrate the developmental, genetic, and imaging spectrum of malformations of cortical development (MCD) from fetal life through adolescence by integrating principles of normal corticogenesis, key genetic pathways, and evolving MRI patterns. This exhibit emphasizes: 1. Normal neuronal proliferation, migration, and post-migrational organization. 2. Developmental stage–specific MRI features linked to corresponding disruptions in these processes. 3. Major molecular pathways (LIS1/DCX, TUBB2B, MCPH1, CDK6, PIK3, PTEN, HEPACAM, mTOR) associated with characteristic imaging phenotypes. 4. The role of longitudinal imaging in evaluating cortical maturation, prognosis, and presurgical planning. Read More

Meeting name: SPR 2026 Annual Meeting , 2026

Authors: Sahu Asutosh, Tripathy Priyadarshini, Kandemirli Sedat, Prabhu Sanjay

Keywords: Magnetic Resonance Imaging, Genetics, Epilepsy