Dual-Energy CT–Based Perfusion Imaging of the Lungs in Children: Acquisition Technique, Post-processing, and Interpretation
Purpose or Case Report: Background: Dual source dual-energy CT scanners (DECT) has allowed for the collection of two data sets with a single scan, opening the potential for functional data acquisition. The technique combines two energy beams at distinct voltages applied concurrently during a single scanning phase. The source data can be combined to generate a single mixed composite image, or iodine can be subtracted to create a contrast map or a virtual non-contrast image. The result is functional information in the setting of decreased radiation dose when replacing a biphasic scan, or dose neutral when compared to conventional single source CT. Post processing lung perfusion software allows for imaging display (qualification) and quantification of iodinated contrast volumes in the lungs, a surrogate for lung perfusion. Purpose: This educational exhibit will demonstrate: 1. How to perform DECT in children, 2. How to use postprocessing software, and 3. How to interpret lung perfusion results through clinical examples of current pediatric clinical indications including pulmonary embolism, lung hypoplasia, pulmonary AV malformation, and pulmonary hypertension. Conclusion: Through this exhibit, readers will gain familiarity with technical aspects of DECT of the lungs in children, understand the basics of post processing and recognize focal or regional perfusion defects, segmented perfusion analysis, and focal lesion perfusion characteristics as well as identify future applications. Methods & Materials: Results: Conclusions:
Rapp, Jordan
( Children's Hospital of Philadelphia
, Philadelphia
, Pennsylvania
, United States
)
Saul, David
( Children's Hospital of Philadelphia
, Philadelphia
, Pennsylvania
, United States
)
Kaplan, Summer
( Children's Hospital of Philadelphia
, Philadelphia
, Pennsylvania
, United States
)
Barrera, Christian
( Children's Hospital of Philadelphia
, Philadelphia
, Pennsylvania
, United States
)
Otero, Hansel
( Children's Hospital of Philadelphia
, Philadelphia
, Pennsylvania
, United States
)
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