Purpose or Case Report: The purpose of this review is to provide an overview of applications of Eovist in the pediatric population, as well as pitfalls. We will begin with an introduction on the origins of Eovist and how it and other hepatocyte specific contrast agents (HSCAs) differ from conventional gadolinium based contrast agents (GBCAs). We will then provide a sample of imaging protocols when Eovist is used for hepatic mass evaluation and for biliary indications. We will review benefits of Eovist in characterizing a variety of pediatric hepatic neoplasms, including hepatoblastoma, hepatocellular carcinoma, focal nodular hyperplasia, hepatic adenomas, and regenerative nodules, with mention of pathologies that do not follow traditional patterns (i.e., inflammatory adenomas). After this, we will cover biliary applications, including choledochal cysts, biliary obstruction, and postoperative bile leak. Finally, we will review some limitations of Eovist; notably, we will mention several scenarios where the hepatobiliary phase could not be achieved, and recommendations for how to approach these cases. Methods & Materials: Results: Conclusions:
Shet, Narendra
( Children's National Medical Center
, Washington
, District of Columbia
, United States
)
Flynn, John
( Children's National Medical Center
, Washington
, District of Columbia
, United States
)
Maloney, Ezekiel
( Seattle Children's Hospital
, Seattle
, Washington
, United States
)
Iyer, Ramesh
( Seattle Children's Hospital
, Seattle
, Washington
, United States
)
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