Purpose or Case Report: Many patients with repaired Tetralogy of Fallot (TOF) have right ventricular (RV) volume overload due to pulmonary regurgitation (PR)and would have ventricular deformation as time goes by after repaired surgery. We studied the effect of pulmonary regurgitation on global and regional right ventricular (RV) deformation, and their relationships with conventional diagnostic parameters.
Methods & Materials: Cases of repaired Tetralogy of Fallot with the duration time of 5-15years between surgery and cardiac magnetic resonance(CMR) were enrolled. The main pulmonary regurgitation fraction(PRF), RV volume and RV ejection fraction(RVEF), RV three segments (basal, mid, apical) of radial, circumferential and longitudinal strain were analyzed on CVI⁴⁶(Circle Vascular Imaging, Canada). Independent Sample t test and Pearson correlation were used to analyze the parameters. RVEF is equal or greater than 54% was considered as normal value.

Results: Twenty repaired Tetralogy of Fallot were enrolled in this study, 8 girls and 12 boys, duration time is 10.27±3.52 years. RV basal, mid and apical radial strain were 19.71±9.54（%），19.39±6.84(%)and 37.28±14.92(%) respectively. RVbasal, mid and apical circumferential strain were -11.39±3.89(%), -12.00±3.65(%) and –18.10±4.90(%) respectively. RV global longitudinal strain was -11.18±3.29(%). There was no correlation between PRF and RV strain but RV end diastolic volume (RV EDVi) and stroke volume(RVSVi). Duration time had obvious negative correlation with LVEF but positive correlation with RV EDVi and RV end systolic volume (RV ESVi). Each segment radial and circumferential strain had obvious correlation.

Conclusions: Pulmonary regurgitation fraction will cause right ventricular volume overload and ventricular deformation. RV strain was not found to have correlation with right ventricular volume overload and ventricular deformation in this small group study, but more cases need to be enrolled and control group should be include to compare which will be continued to study.