Mahomed Nasreen

Final Pr. ID: Poster #: EDU-010

Abstract: HIV is a global pandemic. According to the UNAIDS Report on the Global Aids Epidemic 2013, approximately 3.3 million children under the age of 15 years are living with HIV infection globally. Sub-Saharan Africa has the highest burden of disease with 2.9 million of HIV-infected children. HIV has affected the epidemiology of childhood pneumonia, changing the spectrum of pathogens, antimicrobial susceptibility of bacteria and prognostic outcome. More than 70% of HIV-infected children will suffer at least one episode of a pulmonary infection in the course of their illness. The pneumococcal conjugate vaccine (PCV) demonstrated vaccine efficacy of 20% in HIV-uninfected children and 13% in HIV-infected children in South African using WHO standardized chest X-ray interpretation criteria. The chest X-ray remains the most readily available and the commonest imaging modality for childhood pneumonia. A combination of clinical findings with pattern recognition on chest X-ray narrows the differential diagnosis. We present a pictorial review of chest X-ray findings in HIV-infected children due to infectious causes: pulmonary TB, bacterial pneumonia, Pneumocystis jiroveci pneumonia, viral pneumonia and non- infectious causes: immune reconstitution inflammatory syndrome (IRIS), lymphocytic interstitial pneumonia (LIP) and lymphoma.
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Authors:  Mahomed Nasreen

Keywords:  chest X-rays, HIV-infected children