Diaz Eric,  Hor Kan,  Krishnamurthy Ramkumar,  Lee Simon,  Krishnamurthy Rajesh

Final Pr. ID: Paper #: 045

DMD is X-linked cardiac and skeletal myopathy caused by dystrophin protein deficiency with early death by cardiomyopathy. Cardiac magnetic resonance imaging (CMR) with myocardial fibrosis by late gadolinium enhancement (LGE) precedes decline in ejection fraction (LVEF) and may alter management in DMD. Muscle weakness limits ability to perform consistent breath-hold (BH) in traditional LGE sequences. Free-breathing (FB) LGE with motion correction (MOCO) allows improved visualization. We hypothesize that FB LGE with MOCO provides equivalent diagnostic quality with similar scan time to traditional LGE sequence. Read More

Authors:  Diaz Eric , Hor Kan , Krishnamurthy Ramkumar , Lee Simon , Krishnamurthy Rajesh

Keywords:  LGE, MOCO, CMR

Johnston Thomas,  Lee Simon,  Krishnamurthy Ramkumar,  Krishnamurthy Rajesh,  Hor Kan

Final Pr. ID: Poster #: SCI-010

Cardiomyopathy is the leading cause of mortality for Becker Muscular Dystrophy (BMD).Risk stratification is challenging due to the wide variation of cardiomyopathy onset, progression, and severity; with cardiomyopathy developing independent of skeletal myopathy progression. Current guidelines recommend “complete cardiac evaluation” at ten years of age, but do not specify the type of imaging modality. We have been performing cardiac magnetic resonance imaging (CMR) routinely by 10 years of age. We sought to determine the progression of BMD cardiomyopathy during the adolescent years among patients who have evidence of fibrosis by late gadolinium enhancement(LGE). Read More

Authors:  Johnston Thomas , Lee Simon , Krishnamurthy Ramkumar , Krishnamurthy Rajesh , Hor Kan

Keywords:  Cardiomyopathy, LGE