Brown Brandon,  Shea Lindsey,  Marine Megan

Final Pr. ID: Poster #: EDU-017

MRI evaluation of the placenta, and particularly placental vascularity, is a critical yet challenging task for the radiologist. Failure to accurately diagnose ischemic changes or to detect signs of the abnormally invasive placenta can have devastating consequences for both maternal and fetal patients. The radiologist's task is further complicated by the inability to use intravenous contrast.

In this presentation, we outline a 7-point, systematic method for evaluation of the placenta, highlighting key changes in appearance and signal intensity between 1.5T and 3T MR field strength, and also incorporating a novel method for evaluating blood flow within placental parenchyma utilizing a hybrid image derived from (noncontrast) SSFP and SSFSE pulse sequences. Our systematic approach analyzes the following diagnostic criteria: location, presence of deep vessels, presence of enlarged/ectatic vessels, presence of fibrin/blood products, disruption of uterine myometrial signal, focal bulge, and signal irregularity of the bladder dome. Finally, we correlate this diagnostic method with a quantitative scoring system which can further aid with delivery planning and prognostication. Read More

Authors:  Brown Brandon , Shea Lindsey , Marine Megan

Keywords:  MRI, placenta, vasculature

Haddad Sophie,  Curtin Kathrine,  Davis Laura,  Lee Daeyeon,  Hwang Misun

Final Pr. ID: Poster #: SCI-028

Placental insufficiency represents a major challenge in obstetrics, leading to FGR, preeclampsia, and stillbirth. Diagnosis is often delayed until significant fetal compromise has occurred, highlighting an urgent need to develop non-invasive tools for earlier detection. The guinea pig is an ideal translational model, sharing human-like hemomonochorial placentation, but longitudinal assessment remains challenging. We have previously demonstrated the feasibility of terminal CEUS to assess maternal and fetal placental circulation, a critical gap remains in tracking placental changes throughout gestation. The goal of this study was to establish and demonstrate the feasibility of a reproducible protocol for longitudinal multimodal US to characterize the normal temporal evolution of the placenta and its vasculature in a control cohort. This work focuses on acquiring B-mode, Color/Power Doppler, Spectral Doppler, and SWE data across gestation. Read More

Authors:  Haddad Sophie , Curtin Kathrine , Davis Laura , Lee Daeyeon , Hwang Misun

Keywords:  Placenta, Ultrasound

Valdez Quintana Melissa,  Caro Dominguez Pablo,  Grynspan David,  Hurteau-miller Julie,  Davila Jorge,  Moretti Felipe,  Miller Elka

Final Pr. ID: Poster #: SCI-040

Diffusion weighted images (DWI) have the potential to provide valuable information on the diffusion and perfusion properties of the human placenta and therefore has the capability for detection of early developmental fetal anomalies. The purpose of this study was to determine if DWI of the placenta demonstrates differences between fetuses with and without central nervous system (CNS) abnormalities. Read More

Authors:  Valdez Quintana Melissa , Caro Dominguez Pablo , Grynspan David , Hurteau-miller Julie , Davila Jorge , Moretti Felipe , Miller Elka

Keywords:  Placenta, Fetal, DWI, ADC, CNS Abnormalities

Rebollo Polo Monica,  Planas Roman Silvia,  Nadal Alfons,  Perez Cruz Miriam,  Eixarch Roca Elisenda,  Planells Mariana,  Gómez-chiari Marta

Final Pr. ID: Poster #: EDU-025

The growing body of evidence linking placental physiology and brain development has led to the emergence of a new field coined “neuroplacentology” Disease processes affecting the placenta can have a major influence on overall fetal circulatory function and specifically blood flow to the CNS. In addition, the placenta also plays an important role as an endocrine and immune protective organ.
The aim of this review is to describe the main abnormal placental phenotypes according to the 2016 Amsterdam pathological classification and the role of abnormal placenta in neurodevelopmental disorders.
The placenta-mediated mechanisms of perinatal brain injury are varied, ranging from poor protection to hypoxia. Read More

Authors:  Rebollo Polo Monica , Planas Roman Silvia , Nadal Alfons , Perez Cruz Miriam , Eixarch Roca Elisenda , Planells Mariana , Gómez-chiari Marta

Keywords:  Placenta, Fetal Brain MRI, IVIM

Qu Feifei,  Qian Zhaoxia,  Yadav Brijesh,  Romero Roberto,  Haacke E.,  Sun Taotao,  Patwardhan Sanjay,  Patwardhan Manasi,  Jaiman Sunil,  Jellal Pavan,  Mody Swati,  Marin Concha Julio,  Jiang Ling

Final Pr. ID: Paper #: 106

Both placental vascular density and oxygenation can indicate placenta health. MRA is a powerful tool to evaluate tissue vasculature but with limited applications because of the use of contrast agents. T₂* maps can be used to estimate the placental oxygen reserve. In this work, we acquired non-contrast enhanced MRA and T₂* maps to evaluate placental vasculature and oxygenation. Read More

Authors:  Qu Feifei , Qian Zhaoxia , Yadav Brijesh , Romero Roberto , Haacke E. , Sun Taotao , Patwardhan Sanjay , Patwardhan Manasi , Jaiman Sunil , Jellal Pavan , Mody Swati , Marin Concha Julio , Jiang Ling

Keywords:  Placenta, MRA, T2* mapping

Sarrami Amir Hossein,  Rubesova Erika

Final Pr. ID: Poster #: EDU-031

Placenta, one of the least understood human organs, is external to fetal body with genetic characteristics identical to the fetus. Placenta is made up of its parenchyma, membranes, and umbilical cord (UC). It involved in the transfer blood gases and nutrients, act as immune barrier, secrete hormones and other substances. Ultrasound, Doppler, and MRI are used to evaluate placental configuration and predict adverse outcomes. MR adds value to fetal and placental sonographic evaluation thanks to its wide field of view and high tissue contrast. Single shot fast spin echo (SSFSE), balanced steady state and T1-W, occasionally DWI, are the most used sequences. We present the spectrum of morphologies and pathologies of the placenta and UC on ultrasound and MRI.
Placental location and shape: Placental location is based on its relationship with the uterus and cervix. The placenta tends to migrate toward the fundus throughout pregnancy. Placental thickness ranges from 2-4 cm. It can be a single structure, bilobed or have an accessory lobe. Variations include circumvallate and placenta membranacea.
Placental signal: Normal parenchyma is intermediate to hyperintense on fluid sensitive images, more homogenous in the second trimester and progressively becoming lobulated and septated. Increased number and size of cotyledons make the placenta more heterogenous.
Placental hemorrhage: Blood pooling and hemorrhage are another cause of placental heterogeneity.
Placental-myometrial Interface: Best seen on steady state, displaying a trilaminar appearance.
Chorionicity: Chorionicity and amnionicity are determined on the first trimester ultrasound. MRI offers a larger field of view for evaluation of the membranes’ attachment and UC in the second and third trimesters.
UC insertion: UC inserted to the center of the placenta. Eccentric insertions, and velamentous insertions can be identified on MRI.
UC structure: The UC contains two umbilical arteries, a single umbilical vein, allantois duct and Wharton's jelly and is enclosed within the outer layer of amnion.
UC varix: This refers to the dilation of the fetal umbilical veins as it runs through the fetal abdomen.
UC cysts: Uncommon, differential diagnosis includes pseudocysts, omphalomesenteric duct cysts, vascular disorders, abdominal wall defects, bladder exstrophy and urachal anomalies.
Placental Tumors. Placental tumors are categorized in trophoblastic and non-trophoblastic. The latter include chorioangiomas, teratomas, and hemangiomas. Read More

Authors:  Sarrami Amir Hossein , Rubesova Erika

Keywords:  Placenta, Fetal MRI, Ultrasound

Alici Davutoglu Ebru,  Arioz Habibi Hatice,  Ozel Aysegul,  Yuksel Aytac,  Adaletli Ibrahim,  Madazli Riza

Final Pr. ID: Poster #: SCI-017

To utilize and investigate the value of SWE in cases of placenta previa-accreta and also to evaluate the value of ultrasonography and MRI in the prenatal prediction of morbidly adherent placenta. Read More

Authors:  Alici Davutoglu Ebru , Arioz Habibi Hatice , Ozel Aysegul , Yuksel Aytac , Adaletli Ibrahim , Madazli Riza

Keywords:  placenta previa, shear wave elastography, placenta accreta