Showing 2 Abstracts.
Alternative Approaches to Nusinersen (Spinraza) Administration for Spinal Muscular Atrophy in Patients with Extensive Spinal Hardware
Willard Scott, Kaye Robin, Schaefer Carrie, Aria David
Final Pr. ID: Poster #: EDU-060
To describe alternative routes of Nusinersen administration in patients in whom traditional lumbar puncture is limited secondary to spinal hardware and bony fusion. Read More
Authors: Willard Scott , Kaye Robin , Schaefer Carrie , Aria David
Keywords: Spinraza, Spinal muscular atrophy SMA, nusinersen
Intrathecal Access in Spinal Muscular Atrophy Patients with Scoliosis and Complex Spinal Hardware Including the Trans-Forminal Approach
Patel Manish, Weiss Judith, Kandil Ali, Johnson Neil
Final Pr. ID: Poster #: SCI-034
Patients with Spinal Muscular Atrophy (SMA) may have scoliosis requiring spinal hardware for spinal fixation. The scoliosis in addition to the spinal hardware makes intrathecal access difficult with conventional approaches. With recent FDA approval of nusinersen (SpinrazaÒ) for SMA, intrathecal access is required for administration of this meditation. We describe our experience in these patients using a variety of lumbar puncture approaches (intra-spinous process, trans-pedicle, and trans-foraminal) utilizing conventional fluoroscopy, cone-beam CT (CBCT) with fluoroscopy overlay and/or conventional CT with CT fluoroscopy. Approach to the type of access and image guidance is based on the presence of spinal hardware and degree of scoliosis and spinal fusion. Read More
Authors: Patel Manish , Weiss Judith , Kandil Ali , Johnson Neil
Keywords: Spinal Muscular Atrophy, Lumbar Puncture, Spinraza