To describe alternative routes of Nusinersen administration in patients in whom traditional lumbar puncture is limited secondary to spinal hardware and bony fusion. Read More

Meeting name: SPR 2018 Annual Meeting & Postgraduate Course , 2018

Authors: Willard Scott, Kaye Robin, Schaefer Carrie, Aria David

Keywords: Spinraza, Spinal muscular atrophy SMA, nusinersen

In 2014, 3 patients including a 28-week preemie, 18 day-old neonate, and 11 month-old infant, were treated for large hepatic AVMs. Symptoms included CHF in both the 890-gram preemie and neonate and no symptoms in the infant with imaging revealing extensive shunting. Embolization of the AVMs was performed using various agents, entry sites, and arterial and venous techniques. Agents utilized included detachable and non-detachable coils and vascular plugs. Both direct puncture and intra-vascular techniques, including the use of the umbilical artery, were utilized. Immediate hospital course and short-term clinical and radiographic follow-up was conducted. Technical success was achieved in all 3 patients without immediate complications. The two symptomatic patients improved clinically on short-term follow up with resolution of the preemie’s and neonate’s CHF, confirmed on post-embolization imaging. Conventional angiography demonstrated complete resolution of the AVM in the infant. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Schaefer Carrie, Aria David, Beydoun Tammam, Kaye Robin, Towbin Richard

Keywords: Hepatic AVM, Venous Embolization