To describe alternative routes of Nusinersen administration in patients in whom traditional lumbar puncture is limited secondary to spinal hardware and bony fusion. Read More

Meeting name: SPR 2018 Annual Meeting & Postgraduate Course , 2018

Authors: Willard Scott, Kaye Robin, Schaefer Carrie, Aria David

Keywords: Spinraza, Spinal muscular atrophy SMA, nusinersen

Transcatheter Aortic Valve Replacement (TAVR) is widely becoming an accepted therapy for aortic stenosis. In the last 10 years, estimates place the deployment of TAVRs as high as 50,000 worldwide. Differences in size and morphology of the aortic root and surrounding anatomy are important considerations in determining which TAVR to deploy. 3D printing based off of patient images can be leveraged to create models for patient-specific surgical planning purposes. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Ryan Justin, Pophal Stephen, Aria David, Towbin Richard

Keywords: Transcatheter Aortic Valve Replacement (TAVR), 3D Printing

Educational simulators provide a means for students and experts to learn and refinesurgical skills. Our objective was to develop a cost-effective, patient-derived medical simulacrum for cerebral lateral ventriculostomy. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Ryan Justin, Pophal Stephen, Aria David, Towbin Richard

Keywords: 3D Printing, Anatomical Modeling, Ventriculostomy

In 2014, 3 patients including a 28-week preemie, 18 day-old neonate, and 11 month-old infant, were treated for large hepatic AVMs. Symptoms included CHF in both the 890-gram preemie and neonate and no symptoms in the infant with imaging revealing extensive shunting. Embolization of the AVMs was performed using various agents, entry sites, and arterial and venous techniques. Agents utilized included detachable and non-detachable coils and vascular plugs. Both direct puncture and intra-vascular techniques, including the use of the umbilical artery, were utilized. Immediate hospital course and short-term clinical and radiographic follow-up was conducted. Technical success was achieved in all 3 patients without immediate complications. The two symptomatic patients improved clinically on short-term follow up with resolution of the preemie’s and neonate’s CHF, confirmed on post-embolization imaging. Conventional angiography demonstrated complete resolution of the AVM in the infant. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Schaefer Carrie, Aria David, Beydoun Tammam, Kaye Robin, Towbin Richard

Keywords: Hepatic AVM, Venous Embolization

3D mDIXON Gradient Echo (GRE) technical superiority has already been established: improved fat saturation, faster acquisition time, high spatial resolution, and volumetric data acquisition allowing for a comprehensive multiplanar and 3D post-contrast evaluation of vessels and soft tissue lesions. Vascular malformation imaging requires large field of view images that can adversely affect fat saturation, is frequently performed with a non-sedated patient resulting in motion artifact, and requires higher spatial resolution to better characterize a lesion and evaluate lesion extent. Additionally the interventional radiologists at our institution prefer 3D post-contrast imaging to assist in treatment planning. We believe that this sequence is well suited for vascular malformation MRI imaging. The primary purpose is to illustrate the clinical utility and superior image quality of the 3D mDIXON GRE sequence over more conventional mDIXON TSE sequence through a series of cases of a variety of vascular malformations in different body regions. The secondary purpose of this presentation is to validate the clinical superiority of this sequence through a blinded reviewer comparison to the more conventional mDIXON TSE sequence. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Dance Logan, Keehn Brian, Patel Mittun, Pokorney Amber, Peterson Michael, Aria David, Barnes Craig, Bailey Smita

Keywords: vascular malformation, MRI, water fat imaging