Hutt Airyn,  Shaffer Laura,  Chandra Tushar,  Hayes Laura

Final Pr. ID: Poster #: SCI-024

The growing skeleton has a radiographically different appearance from an adult’s until late adolescence when the physes fuse. If unfamiliar with recognizing these differences on a radiograph, it is common for normal variants to be misinterpreted as fractures and referred to subspecialty orthopedic care. The arising consequences are avoidable; however, to educate caregivers providing interpretations of pediatric orthopedic radiographs we must first understand why and how often these misinterpretations occur. Read More

Authors:  Hutt Airyn , Shaffer Laura , Chandra Tushar , Hayes Laura

Keywords:  Radiography, Normal Variants, Misinterpretations

Boyd Kevin,  Thakrar Pooja

Final Pr. ID: Poster #: EDU-055

The purpose of the exhibit is: 1. Illustrate the presence of multiple and accessory ossification centers about the hip that can make it challenging to diagnosis fractures on radiographs in adolescence. 2. Demonstrate that posterior acetabular fractures are typically hidden behind the femoral head on radiographs. 3. Review variant os acetabuli that are commonly encountered in patients with hip pain and demonstrate that the orientation of the fragments compared with posterior acetabular fractures can help to make a distinction. 4. Highlight that a complete pelvis radiograph (AP or AP/Frog leg lateral) in trauma patients or hip pain NOS can aid in the detection of fractures and assess for asymmetry of normal variants. Read More

Authors:  Boyd Kevin , Thakrar Pooja

Keywords:  Acetabular Fractures, Pediatric Hip, Hip variant

Yadav Vikas,  Sudhakar Sniya,  Thomas Maya,  Arunachal Gautham

Final Pr. ID: Poster #: CR-072

A 1-year-old boy with uneventful perinatal history, non-consanguineous parentage presented with global developmental delay. Family history was not contributory. There was no history suggestive of visual or hearing loss, seizures, bladder and bowel involvement or extrapyramidal symptoms. On examination, Head size was large for age with hyper pigmented nevi over right arm. There was delay involving language, motor and cognition. CNS examination revealed stance ataxia with generalized hypotonia. No obvious organomegaly was noted on abdominal examination.
MRI done in August 2014 showed signal abnormality in dorsal brainstem, dentate nuclei, bilateral thalami and basal ganglia. Gyri appeared swollen with subcortical U fiber involvement. Central white matter was spared. MRS revealed elevated borderline elevation of NAA and lactate. CT did not reveal any obvious calcification in these areas.
Based on these findings differential diagnosis of mitochondrial etiology and L2 hydroxyglutaric aciduria were considered. However, urine tests for routine organic acids were negative.
Literature search revealed findings fitting into Canavan variant disease. Consequently, urine examination showed elevated N acetyl aspartate. The ASPA gene mutation was confirmed on genetic testing.
Another case showed similar clinical presentation. However head size was normal in second case. Imaging findings were similar in nature. Genetic mutation confirmed the diagnosis.
Recognition of the Canavan Variant is important, as most of the cases would be diagnosed as mitochondrial (Leigh’s/ LBSL) or L2 hydroxyglutaric aciduria initially. This pattern recognition lead to correct genetic testing and diagnosis. Read More

Authors:  Yadav Vikas , Sudhakar Sniya , Thomas Maya , Arunachal Gautham

Keywords:  Canavan disease, Variant, N acetyl aspartate, ASPA gene

Hwang Misun,  Servaes Sabah

Final Pr. ID: Poster #: EDU-088

Many normal variants in the skeletal survey can be misconceived as signs of child abuse. Accurate differentiation between the two is crucial in subjecting only the perpetrators to trial. The present exhibit educates on the radiographic signs and techniques that can help differentiate between normal variants and child abuse on the skeletal survey. Read More

Authors:  Hwang Misun , Servaes Sabah

Keywords:  Child abuse, Skeletal Survey, Normal variants

Yaya Carlos,  Fanney Lewis,  Taragin Benjamin,  Nguyen Jie

Final Pr. ID: Poster #: EDU-063

This educational exhibit provides a comprehensive review of normal anatomical variants in the developing pediatric knee, emphasizing the imaging distinctions from pathology to aid radiologists in accurate diagnosis and care. Read More

Authors:  Yaya Carlos , Fanney Lewis , Taragin Benjamin , Nguyen Jie

Keywords:  Normal variants, Pediatrics, Knee