Pulmonary lesions have been found in fewer than 10% of children with a solitary site of involvement in Langerhans cell histiocytosis(LCH) but in 23%–50% of those with multisystem involvement. The established diagnostic procedures are lung biopsy and bronchoalveolar lavage with a score of more than 5% CD1a-positive cells. Scattered reports of LCH within the thymus exist, typically among children within the setting of multifocal, multisystem disease. Purpose of this presentation is overview of the diverse radiologic manifestations of lung and thymic involvement of Langerhans cell histiocytosis that may be observed with imaging, which allows exact depiction of the extent and severity of disease.
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Meeting name:
SPR 2017 Annual Meeting & Categorical Course
, 2017
Authors:
Guleryuz Handan,
Turkan Yilmaz Inci,
Salman Muhammet
Keywords:
langerhans cell histiocytosis