Wolman disease is a rare autosomal recessive inherited disease characterized by storage of cholesterol esters and triglycerides in lysosomes due to a deficiency of lysosomal acid lipase. Clinical signs such as persistent vomiting, diarrhea, hepatosplenomegaly, growth retardation and liver dysfunction occur in the first weeks of life. Most cases die in the first year of life. Here, we aim to present radiological findings of Wolman disease. An asymptomatic girl two months of age was admitted to the pediatric genetic disease service with the history of Wolman disease in two brothers who had died in the neonatal period. Abdominal X-ray imaging displayed calcification of the bilateral adrenal gland regions. Hepatosplenomegaly and bilateral adrenal gland posterior acoustic shadowing due to calcifications were revealed by abdominal sonography. Magnetic resonance imaging showed enlarged hypointense adrenal glands in all sequences and hepatosplenomegaly. The lysosomal acid lipase levels were low compatible with Wolman disease. Multimodality radiologic imaging methods should be performed to display hepatosplenomegaly, hepatosteatosis, bilateral adrenal gland enlargement and calcification in Wolman disease. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Aslan Mine, Kalyoncu Ucar Ayse, Arioz Habibi Hatice, Namdar Yesim, Kurugoglu Sebuh, Adaletli Ibrahim

Keywords: Wolman Disease, Sonography, Adrenal gland, calcification, magnetic resonance imaging

Sacrococcygeal teratoma (SCT) is one of the most common tumors of the newborn. SCT is seen frequently in the presacral region and in forms of solid or mixed solid and cystic masses. Only 10-15 % of all sacrococcygeal teratomas are in pure cystic form. Here, in this case, we aimed to present sonographic and magnetic resonance images (MRI) of a newborn with pelvic cystic mass and bilateral hydronephrosis that were seen on prenatal ultrasonography. An operation was planned for two days of age girl patient for cystic pelvic mass and bilateral hydronephrosis detected by prenatal sonography during the third trimester. On her abdominal X-ray radiography, there was no bowel gas at the midline pelvis. The patient was referred to the sonography unit with the suspicion of a duplication cyst. Abdominal sonography revealed bilateral hydroureteronephrosis, bladder wall thickening, and a 75x55x32 mm pure cystic mass located between the rectum and bladder. The mass had a fine septa at the inferior site. Abdominal MRI showed that the mass had no connection with the spinal canal or solid component. The patient was operated and the diagnosis of purely cystic sacrococcygeal teratoma was confirmed histopathologically. Anterior meningocele, tail gut cyst, rectal duplication cyst, and cystic sacrococcygeal teratomas are common lesions of the presacral region diagnosed in the prenatal or antenatal period. Sacrococcygeal teratoma should be kept in mind in patients with presacral cystic mass in the neoatal period and radiologic methods are helpful for displaying the extent and content of a cystic mass. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Aslan Mine, Arioz Habibi Hatice, Kalyoncu Ucar Ayse, Namdar Yesim, Adaletli Ibrahim, Kurugoglu Sebuh

Keywords: Sacrococcygeal teratoma, Sonography, Magnetic resonance imaging, Neonatal

The diagnosis of Wilms tumor and adrenal gland neuroblastoma can be challenging, even with imaging methods such as computed tomography and magnetic resonance imaging (MRI). This study aimed to show the utility of diffusion weighted MRI (DW-MRI) in the differentiation of neuroblastoma and Wilms tumor. Read More

Meeting name: IPR 2016 Conjoint Meeting & Exhibition , 2016

Authors: Aslan Mine, Arioz Habibi Hatice, Kalyoncu Ucar Ayse, Ozmen Evrim, Aslan Ahmet, Bakan Selim, Yildirim Onur, Kurugoglu Sebuh, Adaletli Ibrahim

Keywords: Wilms tumour, Neuroblastoma, Diffusion weighted imaging, Apparent diffusion coefficient