Hypoxic Ischemic Encephalopathy (HIE) occurs in 1-6/1000 livebirths often leading to death or neurological disability. Neonatal brain magnetic resonance imaging (MRI) is used to assess severity of brain injury and provide prognostic information in the newborn period. However, 20-50% HIE patients do not have early abnormal MRI findings detected by qualitative neuroradiologic evaluation and yet have adverse outcomes evident by 2 years of age. Our aim was to investigate whether quantitative MRI analysis can find subtle abnormalities that help improve prognostication and reduce the incidence of falsely reassuring neonatal MRI among infants with HIE.
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Meeting name:
SPR 2020 Annual Meeting & Postgraduate Course
, 2020
Authors:
Vyas Rutvi,
Morton Sarah,
Nunes Deivid,
Song Yanan,
Grant Ellen,
Ou Yangming
Keywords:
HIE,
neonates,
Quantitative MRI