Showing 4 Abstracts.
As more pediatric patients are infected with severe acute respiratory syndrome coronavirus 2 during the coronavirus disease 2019 (COVID-19) pandemic, more have been diagnosed with multisystemic inflammatory syndrome in children (MIS-C). Early research investigations into MIS-C show cardiac involvement presenting as elevated troponins, ventricular dysfunction, electrical conduction abnormalities, and pericardial effusions. MIS-C may result in myocardial perfusion defects visualized with nuclear medicine imaging and magnetic resonance imaging (MRI), however these perfusion defects on contrast enhanced computed tomography (CT) have not yet been described. Read More
Meeting name: SPR 2022 Annual Meeting & Postgraduate Course , 2022
Authors: Simmons Curtis, Goncalves Luis, Southard Richard, Bardo Dianna
Pediatric abdominal trauma can be challenging and often necessitates rapid and accurate identification of injuries for optimal patient care. This study aimed to assess the potential workflow improvements in diagnostic accuracy achieved with semi-automated analysis of Dual Energy CT (DECT) image reconstruction in the setting of abdominal solid organ injury, as compared to conventional Multi-Detector CT (MDCT) images. The data sets from dual energy reconstructions have superior tissue differentiation and can be used to train a simple artificial intelligence (AI) program to recognize these patterns and expedite care. Read More
Meeting name: SPR 2024 Annual Meeting & Postgraduate Course , 2024
Authors: Griffin Walter, Simmons Curtis, Southard Richard, Jorgensen Scott, Van Tassel Dane
Keywords: Dual Energy, abdominal trauma
Kagami-Ogata syndrome (KOS) is a rare and potentially underdiagnosed imprinting disorder caused by paternal uniparental disomy for chromosome 14 or microdeletions and epimutations involving differentially methylated regions (DMRs) at 14q32.2. Depending on phenotypic expression, KOS may mimic trisomy 18 and asphyxiating thoracic dysplasia. Therefore, awareness is essential for prenatal diagnosis. Coat hanger ribs as seen by x-rays have been reported as s pathognomonic sign but have not been reported prenatally. Herein we present images of the coat hanger ribs as seen by low-dose computerized tomography (CT) as well as detailed imaging of the multiple phenotypic features by ultrasound and MRI of KOS in two cases seen prenatally. Case 1: G1P0 singleton pregnancy had fetal echocardiogram at 25 weeks due to concern for congenital heart disease, thickened nuchal fold and thickened skin of the thoracic wall. The exam showed left superior vena cava draining to coronary sinus, dilated right atrium and right ventricle, total anomalous pulmonary venous return, and hydrops. Skin edema was redemonstrated by follow up US at 29 weeks. Fetal MRI and follow-up US at 32 weeks showed polyhydramnios, diffuse skin edema, prominent cheeks and frontal bossing by 3D US, mild shortening of the ulna and right clubfoot, and a bell-shaped thorax by MRI. Chromosomal microarray was positive for terminal deletion of 14q32.2, consistent with KOS. Coat hanger ribs were present on postnatal x-rays. The patient is G-tube and tracheostomy tube dependent, has global developmental delay, neuromuscular scoliosis, left hip subluxation, wrist contractures and planovalgus feet at the age of 2 ½ years. Case 2: G3P1, singleton pregnancy with negative non-invasive prenatal testing (NIPT). US performed at 29 weeks showed polyhydramnios, clenched hands, and bell-shaped small thorax. Multimodality fetal imagin (US, MRI and CT) at 32 weeks showed a narrowed elongated thorax by US and MRI but ribs were poorly visualized. Additional anomalies included polyhydramnios, rhizomelic bone shortening, clenched hands, and prominent cheeks by 3D US. Low-dose CT showed coat hanger ribs. Postnatal x-rays confirmed coat hanger ribs and other abnormalities. Postnatal genetic testing showed paternal uniparental disomy for chromosome 14, consistent with KOS. The patient has restrictive lung disease due to hypoplastic thoracic cage, hypotonia, scoliosis, developmental delay, and umbilical hernia at 13 months. Read More
Meeting name: SPR 2023 Annual Meeting & Postgraduate Course , 2023
Authors: Goncalves Luis, Patel Mittun, Wermers Josh, Simmons Curtis, Vaughn Jennifer, Pfeifer Cory, Cornejo Patricia
Keywords: kagami-ogata, fetal MRI, fetal CT
Growth in our hospital has resulted in multiple new locations opening which has resulted in staffing by ultrasound technologists lesser experienced in appendicitis imaging. Likewise, our ordering providers have increased their push to reduce CT utilization. Our aim was to improve the appendix visualization frequency by 10% over 6 months to reduce exposure to ionizing radiation, reduce cost for families, lower risk to patients, reduce length of stay in the emergency department, and shorten the time to diagnosis. Read More
Meeting name: SPR 2024 Annual Meeting & Postgraduate Course , 2024
Authors: Sousae Sean, Simmons Curtis, Bailey Smita, Cutler Kayci, Youssfi Mostafa, Reynolds Kristine, Oliver Clay, Pfeifer Cory
Keywords: Appendicitis, Quality Improvement, Ultrasound