Understanding anatomy and embryology is crucial for evaluation of olfactory epithelium, olfactory nerve, olfactory bulb and olfactory cortex pathology. We will discuss various imaging modalities available to evaluate olfactory system and discuss role of fMRI and Diffusion tensor imaging of olfactory system. Fetal MRI can identify olfactory bulb and olfactory sulci after 30weeks of gestation consistently and can be helpful in diagnosis of charge syndrome. Various congenital CNS malformations associated with olfactory system abnormalities like CHARGE, Holoprosencephaly, Kallmann syndrome, Acrocallosal syndrome, frontal encephalocele and sphenoidal encephalocele will be presented. Traumatic injury to cribriform plate of ethmoid can result in transection of olfactory nerve resulting in anosmia. Primary tumors of olfactory epithelium, esthesioneuroblastoma and secondary involvement of olfactory epithelim by rhabdomyosarcoma will be presented. Various tumors that can involve olfactory cortex namely DNET, ganglioglioma and pilocytic astrocytoma will be presented. References: Booth TN, Rollins NK. Spectrum of clinical and associated MR findings in children with olfactory anomalies. Am J Neuroradiol.2016; 37:1541-48 Blustajn J, Krisch CFE, Panigrahy A, Netchine I. Olfactory anomalies in CHARGE syndrome: Imaging findings of a potential major diagnostic criterion. Am J Neuroradiol.2008; 29:1266-69. Read More

Meeting name: SPR 2019 Annual Meeting & Postgraduate Course , 2019

Authors: Lori Schoenbrun, Subramanian Subramanian, Children's Hospital of Pittsburgh , Pittsburgh , Pennsylvania , United States
Rajan Deepa, Gaesser Jenna, Lo Cecilia, Schmithorst Vincent, Panigrahy Ashok

Keywords: Olfactory system, Olfactory sulcus, Olfactory Bulb