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Society for Pediatric Radiology – Poster Archive


Deepa Rajan

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Showing 2 Abstracts.

An 11-year-old female presented with 3-weeks history of intractable vomiting, nausea, blurred vision, vertical nystagmus and ataxia with gait instability. A CT scan revealed a small calcification at the left craniocervical junction (CJJ) and mild effacement of the fourth ventricle (Figure). MRI showed a partially-enhancing medulla oblongata lesion and a non-enhancing cystic exophytic lesion abutting the left pre-medullary cistern. There was avid thick enhancement along the ventrolateral surface of the medulla oblongata. No restricted diffusion was present. MR spectroscopy demonstrated decreased NAA and elevated lactates. Based on imaging findings, a brainstem glioma with exophytic component was suspected. The CBC, CMP, ESR and CRP were normal. The patient underwent suboccipital craniectomy with C1 laminectomy, and an exophytic pale gray mass was identified. Multiple specimens were taken, and frozen diagnosis showed only necrosis. The cyst wall was resected. Resection of the brainstem component was limited by neurophysiology. Histologically, the lesion consisted of a fibrous cyst wall lined by columnar to pseudostratified columnar epithelium, findings reflecting a neuroenteric cyst. No glial tissue was identified. Gram stain and Grocott stain were negative for bacterial and fungal specimens. An empiric treatment with wide spectrum antibiotic was started. Follow-up MRI demonstrated near complete resolution of edema in the medulla oblongata, and substantial decrease in enhancement in anterolateral exophytic component and patient has substantially improved clinically. In retrospect, a sinus tract extended from the cystic lesion at the craniocervical junction into the brainstem causing edema, inflammation and enhancement which resolved once the cyst was surgically decompressed. <b>Conclusion</b>: This case shows a neuroenteric cyst connected to the brainstem, through a sinus tract leading to chronic inflammation and infection, resulting in imaging findings resembling a brainstem glioma. Surgical decompression of the cyst and antibiotic treatment resulted in resolution of the brainstem lesion. Read More

Meeting name: SPR 2018 Annual Meeting & Postgraduate Course , 2018

Authors: Ly Juan Domingo, Subramanian Subramanian, Rajan Deepa, Greene Stephanie, Zuccoli Giulio

Keywords: Neurenteric, magnetic resonance imaging MRI, glioma

Understanding anatomy and embryology is crucial for evaluation of olfactory epithelium, olfactory nerve, olfactory bulb and olfactory cortex pathology. We will discuss various imaging modalities available to evaluate olfactory system and discuss role of fMRI and Diffusion tensor imaging of olfactory system. Fetal MRI can identify olfactory bulb and olfactory sulci after 30weeks of gestation consistently and can be helpful in diagnosis of charge syndrome. Various congenital CNS malformations associated with olfactory system abnormalities like CHARGE, Holoprosencephaly, Kallmann syndrome, Acrocallosal syndrome, frontal encephalocele and sphenoidal encephalocele will be presented. Traumatic injury to cribriform plate of ethmoid can result in transection of olfactory nerve resulting in anosmia. Primary tumors of olfactory epithelium, esthesioneuroblastoma and secondary involvement of olfactory epithelim by rhabdomyosarcoma will be presented. Various tumors that can involve olfactory cortex namely DNET, ganglioglioma and pilocytic astrocytoma will be presented. References: Booth TN, Rollins NK. Spectrum of clinical and associated MR findings in children with olfactory anomalies. Am J Neuroradiol.2016; 37:1541-48 Blustajn J, Krisch CFE, Panigrahy A, Netchine I. Olfactory anomalies in CHARGE syndrome: Imaging findings of a potential major diagnostic criterion. Am J Neuroradiol.2008; 29:1266-69. Read More

Meeting name: SPR 2019 Annual Meeting & Postgraduate Course , 2019

Authors: Lori Schoenbrun, Subramanian Subramanian, Rajan Deepa, Gaesser Jenna, Lo Cecilia, Schmithorst Vincent, Panigrahy Ashok

Keywords: Olfactory system, Olfactory sulcus, Olfactory Bulb