The purpose of this educational exhibit is to give an overview of imaging findings related to the pediatric orbit and optic pathway. Categories of findings include normal anatomy as well as abnormal anatomic variants, prenatal (fetal) as well as congenital/neonatal abnormalities, Infection/Inflammation and neoplastic disease. Read More

Meeting name: SPR 2017 Annual Meeting & Categorical Course , 2017

Authors: Wien Michael

Keywords: orbit, optic pathway

Understanding and identifying cerebral cortical development and related pathology in children is an important skill for interpreting neuroradiology studies. Cortical developmental disease can be broken down into four topics: microcephaly, abnormal cell types, abnormal migration and abnormal cortical organization. After a brief review of cerebral cortex embryology, this educational exhibit will discuss the main pathologies seen in those four categories with illustrative examples from our institution. Outline: I. EMBRYOLOGY A. Formation of the neural plate B. Primary neurulation C. Subdivision of tissues D. Neuron migration E. Neuron organization II. CORTICAL DEVELOPMENTAL DISEASE A. Microcephaly 1) Microcephaly with simplified gyral pattern 2) Microcephaly with thin corpus callosum 3) Microlissencephaly: microcephalic brain with completely smooth, thick cortex. B. Abnormal cell types 1) Focal cortical dysplasia 2) Hemimegaencephaly C. Abnormal migration 1) Cobblestone lissencephaly 2) Classic lissencephaly 3) Incomplete lissencephaly 4) Gray matter heterotopia 5) Periventricular (subependymal) nodular heterotopia 6) Focal subcortical heterotopia D. Abnormal cortical organization 1) Polymicrogyria 2) Schizencephaly III. SUMMARY / CONCLUSION Read More

Meeting name: SPR 2017 Annual Meeting & Categorical Course , 2017

Authors: Dicamillo Paul, Wien Michael

Keywords: cerebral cortex, development