Didier Ryne,  Martin-saavedra Juan,  Sridharan Anush,  Larson Abby,  Coons Barbara,  Coleman Beverly,  Davey Marcus,  Hedrick Holly,  Flake Alan

Final Pr. ID: Paper #: 118

Assessment of fetal brain perfusion with contrast-enhanced ultrasound (CEUS) has not been performed in vivo in congenital diaphragmatic hernia (CDH). The development of the EXTra-uterine Environment for Neonatal Development allows investigation of CEUS and fetal brain perfusion parameters. The purpose of this study was to assess for aberrations in brain perfusion using CEUS in fetal lambs with CDH and correlate with cardiac output data. Read More

Authors:  Didier Ryne , Martin-saavedra Juan , Sridharan Anush , Larson Abby , Coons Barbara , Coleman Beverly , Davey Marcus , Hedrick Holly , Flake Alan

Keywords:  Congenital Diaphragmatic Hernia, Brain Perfusion, Contrast Enhanced Ultrasound

Stern Joseph,  Ramirez Suarez Karen,  Victoria Teresa,  Otero Hansel

Final Pr. ID: Poster #: CR-033

Hepatopulmonary fusion (HPF) is a very rare type of right-sided congenital diaphragmatic hernia (CDH) with a reported prevalence of 3 in 1000 right-sided CDH cases. By June 2020, less than 50 cases have been reported in the literature. Out of 147 patients with right CDH managed at our institution, we found only one case (0.68%) of HPF, which is presented here.

HPF is typically not identified preoperatively, and the presence of HPF changes the operative management. It has been reported that a large right CDH without leftward cardiomediastinal shift and atelectatic lung adherent to the liver are imaging features of HPF.

This patient was a full-term, newborn girl with a normal prenatal course who developed respiratory distress immediately after birth. Chest radiograph at birth demonstrated a right CDH. On day four of life, the patient underwent surgical repair of right CDH. During the procedure, hepatopulmonary fusion involving the cephalad portion of the liver was discovered. The lung and liver could not be separated safely so the diaphragmatic defect was closed around the portion of the liver that extended into the thorax. Postoperative CT angiography of the chest and abdomen demonstrated no abnormal vascular communication between the lungs and liver; however, anomalies of systemic veins were identified. Follow-up chest radiograph at 9 months of age demonstrated a large right CDH that did not include bowel or right-sided colon and was without leftward mediastinal deviation. Concurrent contrast-enhanced CT images of the thorax at this time confirm the right CDH with herniated liver occupying most of the right hemothorax and expected rightward traction of the liver vasculature. However, no significant leftward mediastinal deviation was noted. A small amount of atelectatic lung overlying the liver was also noted, another imaging sign expected with HPF. Last follow-up at age 4, patient was thriving with normal growth and development. Read More

Authors:  Stern Joseph , Ramirez Suarez Karen , Victoria Teresa , Otero Hansel

Keywords:  Hepatopulmonary Fusion, Congenital diaphragmatic hernia, CTA

Kim Wendy,  Courtier Jesse,  Morin Cara,  Shet Narendra,  Strauch Eric,  Kim Jane

Final Pr. ID: Poster #: EDU-035

Late-presenting or recurrent diaphragmatic defects can pose a diagnostic challenge due to varying clinical presentations. Current diagnostic approaches include plain film radiograph for initial assessment, with other imaging modalities such as fluoroscopy, ultrasound, CT and MRI mainly employed for troubleshooting. As a radiation-free modality, MRI can provide a more definitive diagnosis in particular cases due to its ability to visualize discontinuity of the diaphragm (distinguishing it from eventration), hernia contents, defect location and size.

In this exhibit, we will:
1. Review the normal appearance of the diaphragm.
2. Share our institutional MRI protocol for optimal evaluation of the diaphragm, including use of CINE steady state free precession sequences and use of negative slice spacing in T2 weighted images.
3. Discuss important postnatal MR imaging findings of late presenting and recurrent diaphragmatic hernias in children.
4. Describe potential diagnostic pitfalls in the imaging of the diaphragm. Read More

Authors:  Kim Wendy , Courtier Jesse , Morin Cara , Shet Narendra , Strauch Eric , Kim Jane

Keywords:  Diaphragmatic hernia, MRI, Hiatal hernia, Bochdalek hernia, Morgagni hernia

Alford Raphael,  Rubesova Erika,  Halabi Safwan,  Blumenfeld Yair,  Hintz Susan,  Barth Richard

Final Pr. ID: Poster #: SCI-049

The purpose of this study is to determine the reliability of sonographic (US) lung measurements compared with Fetal MR in fetuses with congenital diaphragmatic hernia. The sonographic lung head ratio (LHR) is a widely used prognostic tool in CDH, but can be difficult to obtain due to shifted mediastinum and fetal position. To our knowledge, comparison of MRI measured LHR with US has not been previously reported. Read More

Authors:  Alford Raphael , Rubesova Erika , Halabi Safwan , Blumenfeld Yair , Hintz Susan , Barth Richard

Keywords:  Congenital diaphragmatic hernia, Lung head ratio, LHR, Fetal MRI, Lung volumes