The ability to provide quick, real-time, easily accessible and radiation free diagnostic assessment makes ultrasound (US) imaging one of the most versatile imaging modalities. With the introduction and development of microbubble based ultrasound contrast agents (UCAs) in the early 90’s the ability to detect and visualize complex vascular structures became a reality, overcoming some of the limitations that were existent with grayscale and Doppler imaging. UCA’s are used extensively in the adult population for visualization of vasculature and evaluating vascular kinetics in solid organs and lesions. Although contrast-enhanced ultrasound (CEUS) can provide a powerful alternative approach to evaluate various pathologies in the pediatric population that would otherwise require radiation-based computed tomography (CT) or strenuous magnetic resonance imaging (MRI), it is important to understand the interaction between US and the microbubbles to optimize imaging and derive clinically relevant quantitative measures of vascularity. Read More

Meeting name: SPR 2018 Annual Meeting & Postgraduate Course , 2018

Authors: Sridharan Anush, Darge Kassa

Keywords: CEUS, Ultrasound, microbubbles

The purpose of this experiment was to evaluate the correlation between the doppler and intracranial pressure (ICP) and mean arterial pressure (MAP) in a pediatric porcine model of asphyxia-associated cardiac arrest. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Khaw Kristina, Sridharan Anush, Poznick Laura, Kilbaugh Todd, Hwang Misun

Keywords: Contrast Enhanced Ultrasound, Intracranial Pressure

The purpose of this experiment was to evaluate the correlation between the doppler and intracranial pressure (ICP) and mean arterial pressure (MAP) in a pediatric porcine model of asphyxia-associated cardiac arrest. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Khaw Kristina, Sridharan Anush, Poznick Laura, Kilbaugh Todd, Hwang Misun

Keywords: Doppler, Intracranial Pressure

Conventional Doppler US is known to have low sensitivity for the diagnosis of renal artery stenosis (RAS), in particular segmental renovascular disease. This study aims to determine if contrast-enhanced US (CEUS) can quantitatively provide assessment of renal arterial and parenchymal perfusion pre- and post- renal artery angioplasty in children and potentially be used as a follow-up imaging tool. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Smitthimedhin Anilawan, Sridharan Anush, Darge Kassa, Back Susan, Cahill Anne Marie

Keywords: CEUS, Renal Artery Stenosis, Contrast-Enhanced Ultrasound

Contrast-enhanced ultrasound (CEUS) and shear wave elastography (SWE) have been widely studied in adult thyroid disease. However, evaluation of thyroid nodules using these tools in pediatric patients has yet to be published. We aim to evaluate the feasibility and safety of CEUS and SWE for thyroid nodules in children at the time of cytologic biopsy. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Smitthimedhin Anilawan, Krishnamurthy Ganesh, Sridharan Anush, Poznick Laura, Durand Rachelle, Whitaker Jayme, Escobar Fernando, Bauer Andrew, Cahill Anne Marie

Keywords: CEUS, Elastography, Thyroid

Assessment of fetal brain perfusion with contrast-enhanced ultrasound (CEUS) has not been performed <i>in vivo </i>in congenital diaphragmatic hernia (CDH). The development of the EXTra-uterine Environment for Neonatal Development allows investigation of CEUS and fetal brain perfusion parameters. The purpose of this study was to assess for aberrations in brain perfusion using CEUS in fetal lambs with CDH and correlate with cardiac output data. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Didier Ryne, Martin-saavedra Juan, Sridharan Anush, Larson Abby, Coons Barbara, Coleman Beverly, Davey Marcus, Hedrick Holly, Flake Alan

Keywords: Congenital Diaphragmatic Hernia, Brain Perfusion, Contrast Enhanced Ultrasound