Nyalakonda Ramyashree,  Muehe Anne,  Iles Benjamin,  Theruvath Ashok,  Siedek Florian,  Agarwal Vibhu,  Hawk Kristina,  Jeng Michael,  Daldrup-link Heike

Final Pr. ID: Paper #: 148

To compare the detection of lesions between DW-MRI and ¹⁸F-FDG PET/MR for staging and restaging of Langerhans Cell Histiocytosis (LCH), using all clinical outcomes and imaging data as the reference standard. Also, this study will compare the differences between LCH chemotherapy responders and non-responders. Read More

Authors:  Nyalakonda Ramyashree , Muehe Anne , Iles Benjamin , Theruvath Ashok , Siedek Florian , Agarwal Vibhu , Hawk Kristina , Jeng Michael , Daldrup-link Heike

Keywords:  Langerhans Cell Histiocytosis, Diffusion Weighted Imaging, 18F-FDG PET/MR

Poliachik Sandra,  Alessio Adam,  Friedman Seth,  Wright Jason

Final Pr. ID: Poster #: SCI-043

Purpose: The evaluation of epileptic foci with FDG PET can be challenging, particularly when epileptic foci are subtle. We sought to determine if an age-matched database of normative cerebral FDG PET uptake can be used to automatically identify epileptic foci. Read More

Authors:  Poliachik Sandra , Alessio Adam , Friedman Seth , Wright Jason

Keywords:  FDG PET, Epilepsy, Normative atlas

Nahl Daniel,  Nelson Marvin,  Berkovich Rachel,  Goodarzian Fariba,  Lai Lillian

Final Pr. ID: Poster #: EDU-094

The goal of this educational exhibit is to explore the utility of interictal FDG PET brain imaging in the evaluation of intractable, drug-resistant cases of pediatric epilepsy and to clarify its role in pre-surgical seizure focus localization. We will also explore the salient pearls and pitfalls of FDG PET brain imaging. Read More

Authors:  Nahl Daniel , Nelson Marvin , Berkovich Rachel , Goodarzian Fariba , Lai Lillian

Keywords:  FDG PET, Epilepsy, seizure

Jayapal Praveen,  Baratto Lucia,  Rashidi Ali,  Daldrup-link Heike

Final Pr. ID: Poster #: EDU-055

Children with cancer typically require a local MRI scan for primary tumor staging, which is often supplemented by a whole-body PET scan for whole-body staging. Over the past decade, PET-CT was the most widely used modality for whole-body staging across the world. Seven years ago, our team pioneered whole-body 18F-FDG PET-MRI of children with cancer as a "one-stop" alternative with 80% reduced radiation exposure and optimized child-tailored fast and efficient Whole-Body PET/MRI protocols. We then replaced all whole-Body PET/CT studies at our Institution with whole-body PET-MRI as the standard of care for our patients and have performed over 800 Pediatric Whole Body PET MRIs in the last three years.

The purpose of this educational exhibit is to provide a comprehensive review of whole-body PET/MRI technique, imaging patterns in common pediatric malignancies.

The first aim is to briefly explain our Institution's protocol for simultaneous PET/MRI acquisitions. Such simultaneous acquisition results in a convenient, faster, and safer approach for local and whole-body staging in one session. Furthermore, it avoids the need for repetitive anesthesia and imaging and also avoids potential ionizing radiation from PET CTs. The excellent contrast resolution in the MRI provides superior diagnostic detail compared to the CT.

The second aim will present PET/MRI case examples, where either the PET component added value to the MRI or the MRI component added value to the PET, thereby confirming the importance of this integrated hybrid imaging technology. We will present PET/MRI case examples of the following pediatric tumors:
1. Lymphomas:
2. Osseous Sarcomas including Osteosarcoma and Ewing Sarcoma
3. Soft-tissue Sarcomas such as Rhabdomyosarcoma, Desmoplastic small round blue cell tumor. Synovial Sarcoma, Fibrosarcoma, Epithelioid Sarcoma, Alveolar Soft part sarcoma, and Liposarcoma
4. Neuroblastoma
5. Neuroendocrine tumors
6. Malignant Peripheral Nerve Sheath Tumor
7. Germ cell tumors
8. Renal tumors
9. Malignant Liver tumors
10. Langerhan Cell Histiocytosis

As a result of this educational presentation, participants will be able to prescribe a PET/MRI exam for children with cancer, implement tumor-specific protocol modifications, and improve their tumor diagnoses' sensitivity, specificity, and accuracy. Read More

Authors:  Jayapal Praveen , Baratto Lucia , Rashidi Ali , Daldrup-link Heike

Keywords:  PET-MRI, PET, 18F-FDG PET-MRI