Nuruzzaman Farzana,  Ferguson Polly,  Zhao Yongdong,  Sato T Shawn,  Stimec Jennifer,  Iyer Ramesh,  Carbert Andrew,  Paschke Joel,  Potts Lauren,  Zhang Xiaoyue,  Maksymowych Walter

Final Pr. ID: Poster #: SCI-032

The ChRonic nonbacterial Osteomyelitis Magnetic Resonance Imaging Scoring (CROMRIS) consensus-based scoring system was adapted to assess specific features of bone and soft tissue inflammation in MRI of patients with CNO in a web-based interface. The objectives were to evaluate the absolute agreement of components of and summary CROMRIS scores at each body site, and the inter-rater reliability across raters. Read More

Authors:  Nuruzzaman Farzana , Ferguson Polly , Zhao Yongdong , Sato T Shawn , Stimec Jennifer , Iyer Ramesh , Carbert Andrew , Paschke Joel , Potts Lauren , Zhang Xiaoyue , Maksymowych Walter

Keywords:  Whole Body MRI, Chronic Recurrent Multifocal Osteomyelitis

Kato Kambrie,  Mackenzie John,  Phelps Andrew,  Courtier Jesse,  Behr Spencer,  Zapala Matthew

Final Pr. ID: Poster #: SCI-033

Determine the incidence of occult malignancy detected by ¹⁸F-FDG PET-CT and whole body (WB) MRI in children. Read More

Authors:  Kato Kambrie , Mackenzie John , Phelps Andrew , Courtier Jesse , Behr Spencer , Zapala Matthew

Keywords:  whole body MRI, PET CT, paraneoplastic syndrome

Hughes Nicole,  Phelps Andrew,  Meyer Anna,  Courtier Jesse,  Mackenzie John,  Zapala Matthew

Final Pr. ID: Poster #: EDU-042

Accurate diagnosis of venous malformations can be challenging, and confidently diagnosing them is important for accurate treatment. A thorough understanding of the etiology, imaging appearance, and important mimickers of venous malformations is critical for the radiologist to provide an accurate assessment for the clinician. Read More

Authors:  Hughes Nicole , Phelps Andrew , Meyer Anna , Courtier Jesse , Mackenzie John , Zapala Matthew

Keywords:  MRI, venous malformation, Whole body MRI, Blood pool MRI contrast agent

Nichat Vaibhav,  Matzinger Mary Ann

Final Pr. ID: Poster #: EDU-052

Bones are frequent targets of various neoplastic and non-neoplastic disorders, which often present with focal bone pain. Clinicians should be familiar with the workup of a challenging symptom such as focal bone pain, in order to make appropriate referrals to various specialists, order appropriate investigations and tissue sampling workup, and avoid unnecessary prolonged antibiotics course, thereby preventing delay in diagnosis and antibiotics resistance.

Sometimes, results of various investigations are not always discriminatory among infectious, inflammatory, neoplastic and non-neoplastic etiologies. Some of these disorders can be a source of important morbidity and mortality in infants and children. In order to optimize diagnostic accuracy, early detection of diseases, detection of clinically silent lesions, and disease management, it is imperative for radiologists to be familiar with the imaging characteristics of each entity and the proper methods employed in their evaluation. In light of this, whole body imaging may be performed to get highest yield and cost effectiveness.

The purpose of this exhibit is:

■ To discuss the indications and highlight the role of Whole body MRI and Whole Body Bone Scan
■ To describe scan protocols of Whole body MRI and Whole Body Bone Scan
■ To describe the imaging appearance of some of the oncologic and non-oncologic diseases presenting as bone pain
■ To briefly compare Whole body MRI and Whole Body Bone Scan

Illustrative cases from our Radiology Department will be used to demonstrate various entities such as chronic recurrent multifocal osteomyelitis, infections, Langerhans cell histiocytosis, hematological malignancies, and bony metastases. Read More

Authors:  Nichat Vaibhav , Matzinger Mary Ann

Keywords:  Whole Body MRI, Whole Body Bone Scan, Bone Pain

Reyes Recasens Magdalena,  Arenos-abril Jesus,  Doria Andrea

Final Pr. ID: Poster #: EDU-030

Background: Li-Fraumeni Syndrome (LFS) is an autosomal dominant disorder that predisposes individuals to cancer, associated with mutations in the P53 gene. The most common tumors associated with LFS include breast cancer, osteosarcomas and other sarcomas. Less frequent but also seen are brain tumors, adrenocortical carcinomas and leukemia. However, tumors can manifest almost anywhere in the body.
Given the increased cancer risk, close surveillance is imperative for early cancer detection; guidelines recommend annual Whole Body MRI (WB-MRI) surveillance, along with a series of other imaging and laboratory studies. WB-MRI protocols vary across centers. Although the short tau inversion recovery (STIR)/T2-weighted sequence is accurate for early cancer detection, the combination of STIR/T2 and diffusion-weighted (DW) sequences further increases the diagnostic accuracy of MRI, but at the cost of increased scan time.

Teaching Points: In this educational poster, we will show pediatric surveillance MRI scans in patients with LFS where the utilization of DW-MRI was essential for the diagnosis of cancer or associated conditions, not identified by STIR/T2-weighted MRI solely, along with WB-MRI protocols used in different centers with corresponding total scan time.
Our objective is to demonstrate the added value of using DWI in lesion detection justifying the extended scan duration for surveillance of patients with cancer predisposition disorders. Although it may be uncommon to find lesions exclusively on DWI, the relevance of early cancer diagnosis justifies the time and resources invested in performing this sequence.
Table of contents/Outline:
1. WB-MRI protocols for cancer surveillance in pediatric patients with cancer predisposition disorders.
2. Presentation of cases of:
- Discordant results between DWI and STIR/T2 MRI sequences, false-negative results on STIR/T2 solely.
- Concordant results between DWI and STIR/T2 MRI sequences, true-positive results.
3. Examples of artifacts in DW-MRI that may preclude an accurate diagnosis and approaches to avoid or to minimize them. Read More

Authors:  Reyes Recasens Magdalena , Arenos-abril Jesus , Doria Andrea

Keywords:  Whole Body MRI, Cancer, Surveillance Imaging

Sato T Shawn,  Bajaj Manish,  Ferguson Polly

Final Pr. ID: Poster #: EDU-058

Chronic Recurrent Multifocal Osteomyelitis (CRMO) is an auto-inflammatory disease that can affect multiple locations. Whole body MRI is an important tool to help identify subclinical multifocal disease and help monitor disease. As a referral center for CRMO, we have developed a successful CRMO whole body MRI imaging protocol which maximizes diagnostic information while minimizing scanner time. Read More

Authors:  Sato T Shawn , Bajaj Manish , Ferguson Polly

Keywords:  Rheumatology, CRMO, Whole Body MRI