Placental insufficiency represents a major challenge in obstetrics, leading to FGR, preeclampsia, and stillbirth. Diagnosis is often delayed until significant fetal compromise has occurred, highlighting an urgent need to develop non-invasive tools for earlier detection. The guinea pig is an ideal translational model, sharing human-like hemomonochorial placentation, but longitudinal assessment remains challenging. We have previously demonstrated the feasibility of terminal CEUS to assess maternal and fetal placental circulation, a critical gap remains in tracking placental changes throughout gestation. The goal of this study was to establish and demonstrate the feasibility of a reproducible protocol for longitudinal multimodal US to characterize the normal temporal evolution of the placenta and its vasculature in a control cohort. This work focuses on acquiring B-mode, Color/Power Doppler, Spectral Doppler, and SWE data across gestation. Read More

Meeting name: SPR 2026 Annual Meeting , 2026

Authors: Haddad Sophie, Curtin Kathrine, Davis Laura, Lee Daeyeon, Hwang Misun

Keywords: Placenta, Ultrasound