Tsitsiou Yvonne,  Rychik Jack,  Biko David,  Cahill Anne Marie,  Serai Suraj,  Durand Rachelle,  Golberg David,  Glatz Andrew,  Rand Elizabeth,  Wilkins Benjamin,  Witschey Walter,  Dodds Kathryn,  Russo Pierre

Final Pr. ID: Paper #: 071

Fontan–associated liver disease (FALD) is associated with increased risk of liver cirrhosis and hepatocellular carcinoma. Liver biopsy is the current gold standard investigation for diagnosing liver fibrosis. Magnetic Resonance Elastography (MRE) is a non-invasive procedure assessing liver stiffness. To date, only limited published studies are available describing the correlation of MRE and biopsy in Fontan-associated pediatric patients. Further, longitudinal changes in MRE require an increase in hepatic stiffness of >22% to indicate true change in stiffness (95% CI). The purpose of this study is to determine the clinical implication of MRE in FALD.

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Authors:  Tsitsiou Yvonne , Rychik Jack , Biko David , Cahill Anne Marie , Serai Suraj , Durand Rachelle , Golberg David , Glatz Andrew , Rand Elizabeth , Wilkins Benjamin , Witschey Walter , Dodds Kathryn , Russo Pierre

Keywords:  MR Elastography, Fontan, Liver Biopsy

Gondi Keerthi,  Robinson Amie,  Cully Brent,  Reading Brenton,  Theut Stephanie,  Hendrickson Richard,  Reid Kimberly,  Rivard Douglas

Final Pr. ID: Poster #: SCI-032

Ultrasound guided percutaneous liver biopsy is frequently performed in pediatric patients. Published post-biopsy complication rates range between 0.3 - 3.3% according to Society of Interventional Radiology Standards of Practice. Post-biopsy tract embolization has been prophylactically used to theoretically decrease the bleeding risk, but is not the current standard of care at our institution. The goal of this study is to determine if there is a need for prophylactic biopsy tract-embolization after ultrasound guided liver biopsy in the pediatric population.
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Authors:  Gondi Keerthi , Robinson Amie , Cully Brent , Reading Brenton , Theut Stephanie , Hendrickson Richard , Reid Kimberly , Rivard Douglas

Keywords:  Pediatric Liver Biopsy, Embolization

Swenson Zachary,  Kuo-bonde Lydia

Final Pr. ID: Poster #: SCI-018

Non-alcoholic fatty liver disease (NAFLD) is now the most common form of pediatric chronic liver disease. This disease can have profound effects on overall health and is associated with diabetes, heart disease, and an increased risk of hepatocellular carcinoma. The exact pathogenesis of NAFLD remains poorly understood, though it is known to progress to various chronic liver diseases, the most prevalent being hepatic fibrosis. The current gold standard for quantifying fat in the liver is via a core biopsy, which is expensive and carries an inherent risk of morbidity and mortality which makes it unsuitable for screening and monitoring purposes. We propose that MRI can be an effective, fast, and non-invasive method of screening and monitoring pediatric NAFLD. This would allow for earlier diagnosis and monitoring of pediatric NAFLD which would aid in treatment and management of this disease. Read More

Authors:  Swenson Zachary , Kuo-bonde Lydia

Keywords:  Non alcoholic fatty liver disease, Magnetic Resonance Imaging, Liver Biopsy