Uribe Jesus,  Goodarzian Fariba

Final Pr. ID: Poster #: SCI-031

Gadoxetate disodium-enhanced MRI abdomen is the imaging of choice for evaluation of liver lesions. However, in patients with underlying liver dysfunction, uptake and excretion of the hepatobiliary contrast agent is impaired; standard 20-minute delay hepatobiliary phase imaging may be insufficient to characterize hepatic lesions of interest. Our study aims to evaluate the adequacy of standard 20-minute delayed phase hepatobiliary imaging after gadoxetate disodium administration in pediatric patients with liver dysfunction. A secondary objective is to assess the utility of hepatic function laboratory values as a screening tool to identify patients with impaired hepatobiliary excretion in whom hepatobiliary phase imaging at 20 minutes may be inadequate. Read More

Authors:  Uribe Jesus , Goodarzian Fariba

Keywords:  Liver, Eovist, Fontan

Tsitsiou Yvonne,  Rychik Jack,  Biko David,  Cahill Anne Marie,  Serai Suraj,  Durand Rachelle,  Golberg David,  Glatz Andrew,  Rand Elizabeth,  Wilkins Benjamin,  Witschey Walter,  Dodds Kathryn,  Russo Pierre

Final Pr. ID: Paper #: 071

Fontan–associated liver disease (FALD) is associated with increased risk of liver cirrhosis and hepatocellular carcinoma. Liver biopsy is the current gold standard investigation for diagnosing liver fibrosis. Magnetic Resonance Elastography (MRE) is a non-invasive procedure assessing liver stiffness. To date, only limited published studies are available describing the correlation of MRE and biopsy in Fontan-associated pediatric patients. Further, longitudinal changes in MRE require an increase in hepatic stiffness of >22% to indicate true change in stiffness (95% CI). The purpose of this study is to determine the clinical implication of MRE in FALD.

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Authors:  Tsitsiou Yvonne , Rychik Jack , Biko David , Cahill Anne Marie , Serai Suraj , Durand Rachelle , Golberg David , Glatz Andrew , Rand Elizabeth , Wilkins Benjamin , Witschey Walter , Dodds Kathryn , Russo Pierre

Keywords:  MR Elastography, Fontan, Liver Biopsy

Zafar Faizeen,  Trout Andrew,  Palermo Joseph,  Alsaied Tarek,  Dillman Jonathan

Final Pr. ID: Paper #: 046

Portal hypertension is a manifestation of Fontan-related venous congestion and hepatic fibrosis. We studied the prevalence of radiologic evidence of portal hypertension (RP) and its association with Fontan hemodynamics and adverse outcomes. We also tested the validity of the VAST score, used in a prior study, in our population. Read More

Authors:  Zafar Faizeen , Trout Andrew , Palermo Joseph , Alsaied Tarek , Dillman Jonathan

Keywords:  Fontan, Portal Hypertension, Congenital Heart Disease

Almanza-aranda Judith

Final Pr. ID: Poster #: EDU-001 (S)

El circuito Fontan es el resultado de una serie de procedimientos paliativos que resultan en la anastomosis directa de las venas sistémicas a las arterias pulmonares, sin pasar por cavidades cardiacas. Los avances en las técnicas quirúrgicas han llevado a mejorar los resultados a largo plazo y una mayor esperanza de vida en los pacientes con corrección univentricular. Esto se debe en parte a las imágenes preoperatorias que identifican múltiples parámetros correlacionados con los resultados postquirúrgicos. La resonancia magnética cardiaca (RMC) ha sido utilizada con éxito durante años para evaluar pacientes con ventrículo único, es una excelente herramienta no invasiva para evaluar la anatomía, la función ventricular y el flujo. El propósito de este póster educacional es utilizar una presentación gráfica y cargada de imágenes de RMC de pacientes evaluados con circuito Fontan o pre Fontan para familiarizar al lector con las secuencias básicas y avanzadas utilizadas, las características anatómicas identificadas en los diferentes estadios de la cirugía, los cálculos hemodinámicos obtenidos a partir de las secuencias de contraste de fase y los tipos de anatomía linfática en los pacientes evaluados en nuestra institución. Read More

Authors:  Almanza-aranda Judith

Keywords:  Fontan, RMC, Anatomía linfática

Trout Andrew,  Dillman Jonathan,  Alsaied Tarek,  Lubert Adam,  Palermo Joseph,  Lorts Angela,  Khoury Philip

Final Pr. ID: Paper #: 039

The Fontan operation, used to palliate single ventricle congenital heart disease, increases venous pressure in the liver and is associated with Fontan associated liver disease (FALD), for which liver fibrosis is the final common pathway. Elastography (ultrasound [US] or MRI) can be used to non-invasively measure liver stiffness associated with liver fibrosis. However, these measures are confounded in Fontan patients due to venous congestion. The purpose of this study was to prospectively document the stiffening effect of passive hepatic congestion following the Fontan operation and track changes in liver stiffness over the post-operative period. Read More

Authors:  Trout Andrew , Dillman Jonathan , Alsaied Tarek , Lubert Adam , Palermo Joseph , Lorts Angela , Khoury Philip

Keywords:  Fontan, Liver, Ultrasound