Fontan–associated liver disease (FALD) is associated with increased risk of liver cirrhosis and hepatocellular carcinoma. Liver biopsy is the current gold standard investigation for diagnosing liver fibrosis. Magnetic Resonance Elastography (MRE) is a non-invasive procedure assessing liver stiffness. To date, only limited published studies are available describing the correlation of MRE and biopsy in Fontan-associated pediatric patients. Further, longitudinal changes in MRE require an increase in hepatic stiffness of >22% to indicate true change in stiffness (95% CI). The purpose of this study is to determine the clinical implication of MRE in FALD. Read More

Meeting name: SPR 2020 Annual Meeting & Postgraduate Course , 2020

Authors: Tsitsiou Yvonne, Rychik Jack, Biko David, Cahill Anne Marie, Serai Suraj, Durand Rachelle, Golberg David, Glatz Andrew, Rand Elizabeth, Wilkins Benjamin, Witschey Walter, Dodds Kathryn, Russo Pierre

Keywords: MR Elastography, Fontan, Liver Biopsy