Tsitsiou Yvonne, Rychik Jack, Biko David, Cahill Anne Marie, Serai Suraj, Durand Rachelle, Golberg David, Glatz Andrew, Rand Elizabeth, Wilkins Benjamin, Witschey Walter, Dodds Kathryn, Russo Pierre
Final Pr. ID: Paper #: 071
Fontan–associated liver disease (FALD) is associated with increased risk of liver cirrhosis and hepatocellular carcinoma. Liver biopsy is the current gold standard investigation for diagnosing liver fibrosis. Magnetic Resonance Elastography (MRE) is a non-invasive procedure assessing liver stiffness. To date, only limited published studies are available describing the correlation of MRE and biopsy in Fontan-associated pediatric patients. Further, longitudinal changes in MRE require an increase in hepatic stiffness of >22% to indicate true change in stiffness (95% CI). The purpose of this study is to determine the clinical implication of MRE in FALD.
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Authors: Tsitsiou Yvonne , Rychik Jack , Biko David , Cahill Anne Marie , Serai Suraj , Durand Rachelle , Golberg David , Glatz Andrew , Rand Elizabeth , Wilkins Benjamin , Witschey Walter , Dodds Kathryn , Russo Pierre
Keywords: MR Elastography, Fontan, Liver Biopsy