Anand Neil, Tarud Raul, Su Hsiu
Final Pr. ID: Poster #: EDU-002
The purpose of this exhibit is to make radiologists and clinicians aware of the different disease entities, which involve avascular necrosis. Additionally, we will discuss the different locations in which avascular necrosis can occur and the different pathogenic mechanisms which contribute. Avascular necrosis has a wide variety of etiologies and can affect nearly every bone in the human body. Many sites of involvement are given eponyms associated with the corresponding area. These sites are to be discussed individually, as many have unique clinical and prognostic features. We aim to educate radiologists and clinicians regarding the imaging characteristics of avascular necrosis in the various diseases discussed. Read More
Authors: Anand Neil , Tarud Raul , Su Hsiu
Golden Eleza, Simoneaux Stephen, Dickson Paula
Final Pr. ID: Poster #: CR-049
To describe the radiographic appearance of subclinical calcified brown fat necrosis and to delineate the associated clinical and laboratory findings. While brown fat necrosis has been described in infants with underlying cardiac disease treated with prostaglandins, we emphasize hypotension from cardiac or respiratory arrest as a primary risk factor. Read More
Authors: Golden Eleza , Simoneaux Stephen , Dickson Paula
Keywords: fat necrosis, soft tissue calcification, congenital heart disease
Fenlon Edward, Jaramillo Diego, Restrepo Ricardo, Corral Gonzalo
Final Pr. ID: Poster #: EDU-008
Subcutaneous fat necrosis of the newborn (SCFN) is an uncommon disorder predominantly occurring in full-term and post-term neonates during the first 6 weeks of life. Clinically it presents as an area of edema followed by indurated plaques or non-tender and mobile nodules with overlying erythema, typically along the back, buttocks, extremities, or cheeks. SCFN may result from localized tissue hypoxia and mechanical pressure that further compromises the local circulation. Fetal and neonatal conditions including macrosomia, perinatal asphyxia, traumatic birth and therapeutic hypothermia; and several maternal conditions including preeclampsia, hypertension, gestational diabetes, cocaine or cigarette exposure, calcium channel blocker use during pregnancy, and familial dyslipidemia have been associated with SCFN. Although SCFN is a self-limiting condition, patients should be monitored for associated hypercalcemia and its complications such as nephrocalcinosis and nephrolithiasis.
As these lesions are superficial, they are well evaluated with high resolution ultrasound imaging for initial assessment and follow-up. Findings on ultrasound and MRI include lesions confined to the subcutaneous fat sparing the dermis, with indistinct borders lacking a distinct mass. Lesions of SCFN are echogenic on US, intermediate to low signal intensity on T1-weighted sequences, intermediate to high signal on fluid sensitive sequences, and may demonstrate cystic changes.
We will review the imaging findings of subcutaneous fat necrosis in over ten newborns collected from three tertiary care hospitals, with a focus on ultrasound findings. Many of the lesions were multifocal and the majority involved the patient's back. Ultrasound evaluation was performed in all cases. MRI performed in a minority of cases will also be reviewed. While only one case was biopsied for pathologic correlation, each lesion was closely followed clinically. We will also review several mimickers of fat necrosis to be aware of. Read More
Authors: Fenlon Edward , Jaramillo Diego , Restrepo Ricardo , Corral Gonzalo
Keywords: Ultrasound, Fat, Necrosis