Snyder Elizabeth,  Pruthi Sumit,  Hernanz-schulman Marta

Final Pr. ID: Paper #: 121

Before the germinal matrix (GM) begins to recede at approximately 26 weeks gestational age (GA), it extends along the floor of the lateral ventricles far posterior to the thalamocaudate grooves. As extremely premature infants (EPIs) as young as 23 weeks GA survive with current advances in neonatology support, germinal matrix hemorrhage (GMH) can occur along these sites from which the GM has not yet involuted and should be recognized. Further, such Grade I posterior GMH may be mistakenly diagnosed as an intraparenchymal grade IV event, particularly on coronal US or other axial images, with parasagittal images demonstrating the correct diagnosis. The aim of this study is to document and describe this phenomenon, differentiate it from traditional GMH findings, and assess its prevalence in this population. Read More

Authors:  Snyder Elizabeth , Pruthi Sumit , Hernanz-schulman Marta

Keywords:  Ultrasound, Germinal Matrix Hemorrhage, prematurity

Acosta-izquierdo Laura,  Dien-esquivel Maria,  Miller Elka,  Ferretti Emanuela,  Martinez-rios Claudia

Final Pr. ID: Poster #: EDU-016 (S)

Extremely low gestational age (ELGA) infants are those born before 23 + 6 weeks of gestation. These infants are prone to multiple complications. Frequent complications affect the brain. Transfontanellar brain ultrasound (US) is the standard of care imaging modality to assess the brain during the first weeks of life. An appropriate ultrasound technique includes assessment of the brain in gray scale, color and spectral Doppler. Doppler US should be interpreted in correlation with the neonate’s clinical and systemic hemodynamic state, postnatal age, blood gas concentrations, respiratory or cardiovascular complications, amongst others. Prior literature focuses on the sonographic characteristics of premature, near term and term infants. However, Doppler US characterization of the intracranial vessels of ELGA infants is lacking. The purpose of this exhibit is to describe the resistive index (RI) and peak systolic velocities (PSV) of the anterior cerebral artery and the PSV of the superior sagittal sinus of a cohort of ELGA infants, and to assess their correlation with complications encountered in these infants. Read More

Authors:  Acosta-izquierdo Laura , Dien-esquivel Maria , Miller Elka , Ferretti Emanuela , Martinez-rios Claudia

Keywords:  Brain Doppler, Resistive index, Prematurity

Acosta-izquierdo Laura,  Dien-esquivel Maria,  Miller Elka,  Ferretti Emanuela,  Martinez-rios Claudia

Final Pr. ID: Poster #: EDU-017 (S)

Extremely low gestational age (ELGA) infants are those born before 23 + 6 weeks of gestation. Continued advances on therapy and supportive care in the neonatal intensive units have allowed for an improved survival of these infants. Transfontanellar brain ultrasound (US) is the standard of care imaging modality to assess the integrity of the brain during the first weeks of postnatal life, as it provides a closer direct look to the brain. The purpose of this exhibit is to illustrate detailed US characteristics of the normal development and complications of the evolving premature brain of ELGA infants. Read More

Authors:  Acosta-izquierdo Laura , Dien-esquivel Maria , Miller Elka , Ferretti Emanuela , Martinez-rios Claudia

Keywords:  Brain anatomy, Prematurity, Neurodevelopment

Vasung Lana,  Borradori Tolsa Cristina,  Hanquinet Sylviane,  Huppi Petra,  Merlini Laura

Final Pr. ID: Poster #: SCI-004

A spatio-temporal delay in maturation and reorganization of transient fetal compartements, such as subplate zone, Von Monakow segments of white matter, crossroad areas and migrating cell bands, seems to be linked to abnormal brain growth and radial vulnerability(Kostovic et al. 2014) in preterm born infants (PT). The aim of our study was to test the MRI visibility of these transient fetal structures and eventually to compare their appearance patterns in two group of infants: term borns and PT at term equivalent age. Read More

Authors:  Vasung Lana , Borradori Tolsa Cristina , Hanquinet Sylviane , Huppi Petra , Merlini Laura

Keywords:  Transient fetal zones, Subplate zone, Scoring, Prematurity, Fetal white matter

Gunatilaka Chamindu,  Bates Alister,  Higano Nara,  Hahn Andrew,  Fain Sean,  Hysinger Erik,  Fleck Robert,  Woods Jason

Final Pr. ID: Paper #: 035

Tracheomalacia (TM) is a common morbidity associated with prematurity and manifests as dynamic collapse of the trachea lumen due to cyclic changes of intrathoracic pressure during breathing. Premature infants often have elevated work of breathing (WOB) related to their distal, small airway and lung abnormalities. The large airway contribution to WOB can be determined using computational fluid dynamics (CFD), which is a well-known technique to calculate the resistance and WOB in the human airway. However, previous studies are based on static airway geometry without motion. Using the novel technique of ultrashort echo time (UTE) magnetic resonance imaging (MRI), the tidal volume and airway motion can be used to create a dynamic model for use in CFD. Our aim is to calculate the estimated WOB in a dynamic trachea with neonatal TM compared with a stable, static trachea.
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Authors:  Gunatilaka Chamindu , Bates Alister , Higano Nara , Hahn Andrew , Fain Sean , Hysinger Erik , Fleck Robert , Woods Jason

Keywords:  Bronchopulmonary Dysplasia, MRI, Prematurity