Phalangeal micro geodic disease (PMD)/ transient phalangeal osteolysis is a rare self-limiting condition for which there are limited published case reports. There have been an increasing number of cases over the last thirteen years dating back to 2001. We present several paediatric cases diagnosed as PMD over the last ten years and their imaging features, often overlapping with inflammatory or infective arthropathy. PMD has a higher occurrence after cold exposures and thus seen in colder regions. It has also been described to favor the fingers over the toes. This is a pictorial review that highlights the imaging findings of PMD to enable a smoother journey from presentation to diagnosis for both our Radiological and Clinical colleagues. Read More
Meeting name: SPR 2025 Annual Meeting , 2025
Authors: Chotai Heena, Varma Nisha, Liyanage Neelika
Keywords: X-Ray, Magnetic Resonance Imaging, Paediatric Radiology
Hemolytic uremic syndrome (HUS) is a recognized but still uncommon disease with an incidence varying between 1 to 3 cases per 100,000 annually. It consists of a triad of acute renal failure, microangiopathic hemolytic anemia, and thrombocytopenia, with this triad resulting from endothelial cell damage, intravascular hemolysis, platelet activation, and subsequent microthrombi with multi-organ involvement. Classical cases involve a school age child with diarrhea with diarrhea and acute renal failure. This form of HUS is post-infectious from exposure to a Shigella toxin-producing E. coli (STEC) and was previously called typical HUS. A newer understanding of the condition and pathophysiology has brought about changes into the classification, which the radiologist should be aware of. HUS can now be best divided into: - Hereditary HUS (where there are gene-related changes affecting the body’s coagulation regulation) - Acquired HUS, which can be post-infectious (as in STEC, pneumoccous, HIV), from autoantibodies or drug-related. As understanding of the condition has changed, this review aims to bring the imaging features in line for hereditary HUS and acquired HUS. This cross-center educational review will focus on multi-modality and multi-system imaging findings, which have typical features on ultrasound, CT and MRI. It will also highlight differences that occur in the presentation and findings in three large centers that are positioned in different parts of the world. We will focus on early recognition to aid the clinician; however, we will also detail the significant complications in the genitourinary, gastrointestinal, and central nervous systems that can occur. Learning Points: - Understand the evolution of HUS classification and appreciation of how this is important for the radiologist to aid diagnosis. - Learn the imaging findings in classical HUS as well as the rarer forms of HUS, in addition to how these conditions present across different countries. - Appreciation of the use of multimodality imaging to facilitate earlier detection to aid the clinician and child with earlier diagnosis. - Recognition of the multisystem organ involvement and complications associated with HUS. Read More
Meeting name: SPR 2025 Annual Meeting , 2025
Authors: Chotai Heena, Liu Amanda, Durand Rachelle, Courtier Jesse, Davda Sunit
Keywords: Anemia, Renal Failure