Showing 3 Abstracts.
MOGAD varies widely in MRI patterns and has overlapping imaging features with other conditions such as leukodystrophies, infections or other autoimmune diseases. The 2023 MOGAD diagnostic criteria highlights the diagnostic role of MR imaging to diagnose patients that have low positive myelin oligodendrocyte glycoprotein IgG titers or when the titers are not available. This poster aims to review the various MR imaging appearances of Pediatric MOGAD. We will review the most common phenotypes such as ADEM, optic neuritis or longitudinally extensive myelitis but also others not as common, such as brainstem and cerebellar involvement, leukodystrophy-like or cranial and peripheral neuropathy patterns. We will also provide teaching points and some clues for the differential diagnosis, including the discussion of a pathologic slide of a tumefactive case that led to biopsy. Finally, this poster will highlight the importance of ASL to diagnose cortical forms of MOGAD, which may be subtle on conventional sequences but very apparent on perfusion imaging. We certainly believe that this poster may be of great help to familiarize radiologists working in institutions where MOGAD is not commonly encountered. Read More
Meeting name: SPR 2026 Annual Meeting , 2026
Authors: Molto Garcia Jose Francisco, Nair Lakshmi, Kahn Ilana
Keywords: MR, Autoinflammation, Pediatric Neuroradiology
Neurodegeneration with Brain Iron Accumulation comprises a clinically and genetically heterogeneous group of disorders that share the feature of high levels of iron in the basal ganglia. Although very rare, these disorders may be suspected commonly by radiologists when iron deposits in the basal ganglia are encountered. Generally, radiologists are not familiar with the MR phenotypes of these disorders beyond the typical ‘eye of the tiger’, which may lead to overcalling since nonspecific iron deposits in the basal ganglia are way more common than NBIA. The aim of this educational poster is to discuss the MR phenotypes of the four most common NBIA disorders to include BPAN, PKAN, PLAN and MPAN, comprising about 95% of the cases. We will not only review the typical auntminnie presentation but also, we will describe the earliest signs, such as the T2 hyperintense streak along the medial border of the pallidi of PKAN, interestingly before any iron deposition is evident. When available, we will discuss the follow-up cases to see how the patterns evolve over time. Finally, we will briefly review the anatomy of the basal ganglia, subthalamic nuclei, substantia nigra and their connections since it is of the utmost importance for the pattern recognition. We hope that this review helps radiologists recognize the NBIA phenotypes to be more confident in their differentials. Read More
Meeting name: SPR 2026 Annual Meeting , 2026
Authors: Molto Garcia Jose Francisco, Tochen Laura, Rhee Jullie
The main purpose is to depict sonographic features of the subpial hemorrhage of the neonate. Secondary purposes are: (1) Review the anatomy of the subpial space, (2) Review proposed pathophysiology, (3) Demonstrate CT and MR correlates of subpial hemorrhages. Read More
Meeting name: SPR 2022 Annual Meeting & Postgraduate Course , 2022
Authors: Molto Garcia Jose Francisco, Cielma Tara, Rao Jhanavi, Czarniecki Marcin B., Sanchez Ramon
Keywords: Hemorrhage, Ultrasound, Brain